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Uterine Artery Doppler Changes

NCT03064698 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 32

Last updated 2020-10-20

No results posted yet for this study

Summary

In uncomplicated pregnancies, the uterine spiral arteries undergo a series of structural changes that result in a low resistance in the uterine arteries as pregnancy progresses.

In many pregnancies complicated with preeclampsia, growth restriction and other placental related complication, the described change does not occur. In pregnancies at high risk for placental complications, doppler measurement of Uterine artery flow has been shown to be a reliable predictor of complications.

Postpartum there is a reversal of vascular changes seen in normal pregnancies. It is unclear if there is a full reversal of these changes in complicated pregnancies with abnormal flow during pregnancy.

The investigators hypothesize that Doppler uterine artery measurements after complicated pregnancies will show some abnormality compared to doppler measurements following uncomplicated pregnancies.

Conditions

  • Uterine Artery Flow

Interventions

OTHER

Post-partum Doppler ultrasound

Participants will undergo one uterine artery Doppler ultrasound at 6 weeks post-partum.

Sponsors & Collaborators

  • Unity Health Toronto

    lead OTHER

Principal Investigators

  • Howard Berger, MD · Unity Health Toronto

Eligibility

Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-09-01
Primary Completion
2022-09-01
Completion
2022-09-01

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03064698 on ClinicalTrials.gov