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Effect of Pregnancy on Androgenic Steroids in Different Genetic Panels

NCT03064412 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 70

Last updated 2017-07-24

No results posted yet for this study

Summary

Androgens are important sex steroids in women. Androgens influence protein synthesis and muscle growth, are involved in maturation of the reproductive organs, have a fat reducing effect , have a negative effect on the serum lipid profile, and may also increase insulin resistance and coagulation activity. The role of androgens in women is not clear. This study is aimed at learning about the amount of androgen and its actions in pregnant women. This study is also looking to see if there are specific patient factors (such as genetics) that change the amount of androgen and its activity.

Conditions

  • Sex Steroids

Interventions

BIOLOGICAL

Urine sample collection

A urine sample will be collected in each of the 3 trimesters of pregnancy, and also at 6 weeks post partum.

BIOLOGICAL

Saliva collection

A saliva sample will be collected at one time point during the study - likely at the initial baseline visit.

Sponsors & Collaborators

  • Unity Health Toronto

    lead OTHER

Principal Investigators

  • Howard Berger, MD · Unity Health Toronto

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-09-30
Primary Completion
2017-01-31
Completion
2017-01-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03064412 on ClinicalTrials.gov