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Dynamic Monitoring of Circulating microRNA Changes in Patients With or Without Multiple Organ Failure

NCT03059524 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2017-02-23

No results posted yet for this study

Summary

The objectives are to:

1. validate a panel of tissue-specific miRNAs that are differentially expressed in the plasma of patients with and without multiple organ failure.
2. investigate the dysregulation of circulating miRNA panel and their prognostic and predictive values in clinical outcomes in identifying patients at high risk for mortality and multiple organ failure.

This trial involves peripheral blood sampling from subjects at their earliest presentation and remaining stays in the hospitalization in the emergency department. The investigators will develop panels of miRNAs that are specific indicator of early onset of major organ failures, and correlate clinical outcomes with these miRNAs.

Conditions

  • Multiple Organ Failure

Sponsors & Collaborators

  • Chengdu Nuoen Biotechnologies, Inc.

    collaborator OTHER

  • University of Electronic Science and Technology of China

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-01-31
Primary Completion
2018-12-31
Completion
2018-12-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03059524 on ClinicalTrials.gov