A Multiple Dose Study to Assess the Safety and Tolerability of BMS-986166 in Healthy Volunteers
NCT03038711 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 213
Last updated 2019-01-30
Summary
The purpose of this study is to understand if multiple oral doses of BMS-986166 are safe and well tolerated in healthy patients.
Conditions
Interventions
- DRUG
-
BMS-986166
Specified dose on specified days
- OTHER
-
Placebo matching BMS-986166
Specified dose on specified days
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Bristol-Myers Squibb · Bristol-Myers Squibb
Study Design
- Allocation
- RANDOMIZED
- Purpose
- SCREENING
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2017-02-01
- Primary Completion
- 2017-08-10
- Completion
- 2017-08-10
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
GSK2982772 Study in Subjects With Ulcerative Colitis
NCT02903966 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase 3 Study to Investigate the Efficacy and Safety of SHR0302 With Moderately to Severely Active Ulcerative Colitis
NCT05181137 ·Status: UNKNOWN ·Phase: PHASE3
-
A Phase II Study in Patients With Moderate to Severe Active Ulcerative Colitis.
NCT03675477 ·Status: COMPLETED ·Phase: PHASE2
-
Effect of GSK1399686 in Patients With Mild to Moderately Active Ulcerative Colitis
NCT01036022 ·Status: COMPLETED ·Phase: PHASE2
-
A Study To Investigate The Safety And Efficacy Properties Of PF-00547659 In Patients With Active Ulcerative Colitis
NCT00928681 ·Status: COMPLETED ·Phase: PHASE1
-
GB004 in Adult Subjects With Active Ulcerative Colitis
NCT03860896 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy, Safety and Tolerability of AEB071 in Patients With Active, Moderate to Severe Ulcerative Colitis
NCT00572585 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of a Single Dose of ASP3291 in Subjects With Ulcerative Colitis
NCT01320332 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of MK-6194 (PT101) in Participants With Active Ulcerative Colitis (UC) (MK-6194-002)
NCT04924114 ·Status: COMPLETED ·Phase: PHASE1
-
First-In-Human Study of BBT-401-1S Following Single and Multiple Ascending Doses in Healthy Volunteers
NCT03482648 ·Status: COMPLETED ·Phase: PHASE1
-
Safety, Tolerability, Efficacy and Dose-response of GSK2831781 in Ulcerative Colitis
NCT03893565 ·Status: TERMINATED ·Phase: PHASE2
-
A Study to Evaluate Efficacy and Long-term Safety of Oral Ozanimod in Chinese Participants With Moderately to Severely Active Ulcerative Colitis (UC)
NCT05644665 ·Status: TERMINATED ·Phase: PHASE3
-
Study Evaluating ISM5411 Administered Orally to Subjects With Active Ulcerative Colitis (BETHESDA)
NCT07265570 ·Status: RECRUITING ·Phase: PHASE2
-
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AMG 181 in Healthy Subjects and Subjects With Mild to Moderate Ulcerative Colitis
NCT01164904 ·Status: TERMINATED ·Phase: PHASE1
-
An Investigational Study of Experimental Medication BMS-986165 in Participants With Moderate to Severe Crohn's Disease
NCT03599622 ·Status: TERMINATED ·Phase: PHASE2
-
A Study to Evaluate the Safety and Efficacy of Ustekinumab Induction and Maintenance Therapy in Participants With Moderately to Severely Active Ulcerative Colitis
NCT02407236 ·Status: COMPLETED ·Phase: PHASE3
-
Safety and Efficacy of TJ301 IV in Participants With Active Ulcerative Colitis
NCT03235752 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)
NCT06979336 ·Status: RECRUITING ·Phase: PHASE2
-
A Study to Assess the Efficacy and Safety of Afimkibart (Also Known as RO7790121) for Induction and Maintenance Therapy in Participants With Moderately to Severely Active Ulcerative Colitis
NCT06589986 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Nolpitantium Besylate In Patients With Ulcerative Colitis a Double-Blind, Placebo Controlled Efficacy and Safety Study
NCT00232258 ·Status: COMPLETED ·Phase: PHASE2
-
Study to Evaluate the Safety and Efficacy of Two Adalimumab Dosing Regimens in Subjects With Moderate to Severe Ulcerative Colitis
NCT02065622 ·Status: COMPLETED ·Phase: PHASE3
-
Study to Compare Oral PF-06651600, PF-06700841 and Placebo in Subjects With Moderate to Severe Ulcerative Colitis
NCT02958865 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Participants With Moderately to Severely Active Ulcerative Colitis
NCT03653026 ·Status: COMPLETED ·Phase: PHASE3
-
Induction and Maintenance Study of BMS-936557 Patients With Moderate to Severe Ulcerative Colitis
NCT01294410 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of BBT-401-1S in Ulcerative Colitis
NCT03800420 ·Status: TERMINATED ·Phase: PHASE2