Radiation Plus Concurrent Nimotuzumab in Elderly Patients With Locoregionally Advanced Nasopharyngeal Carcinoma
NCT03025958 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2024-05-06
Summary
Radiation Plus Concurrent Nimotuzumab in Elderly Patients With Locoregionally Advanced Nasopharyngeal Carcinoma
Conditions
- Nasopharyngeal Carcinoma
Interventions
- DRUG
-
Nimotuzumab
Concomitant nimotuzumab was given weekly at a dose of 200 mg from one week before the start of IMRT.
- RADIATION
-
Radiation
Briefly, the dose prescribed was 70.4 Gy, 70.4 Gy, 60.8 Gy, and 54.4 Gy in 32 fractions delivered over 6 weeks at the periphery of the planning target volume (PTV)nx+rn, PTVnd, PTV1, and PTV2, respectively, using the simultaneous integrated boost technique.
Sponsors & Collaborators
-
Zhejiang Cancer Hospital
lead OTHER
Principal Investigators
-
Xiaozhong Chen, MD · Zhejiang Cancer Hospital
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-03-13
- Primary Completion
- 2018-11-12
- Completion
- 2023-12-30
Countries
- China
Study Locations
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