Trial Outcomes & Findings for Feasibility Study of the TruSculpt Radiofrequency Device (NCT NCT03018587)

NCT ID: NCT03018587

Last Updated: 2023-03-07

Results Overview

Degree of improvement in the treatment area at 12 weeks post-treatment compared with Baseline photo as assessed by the Investigator using Global Aesthetic Improvement Scale(GAIS): 4 = Very Significant Improvement (\>75%), 3 = Significant Improvement (51 - 75%), 2 = Moderate Improvement (26 - 50%), 1 = Mild Improvement (5 - 25%), or 0 = No Change (\<5%)

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

23 participants

Primary outcome timeframe

12 weeks post-treatment

Results posted on

2023-03-07

Participant Flow

Participant milestones

Participant milestones
Measure
All Subjects
All subjects will receive 1 truSculpt radiofrequency treatment in desired area. TruSculpt: All subjects will receive 1 truSculpt radiofrequency treatment
Overall Study
STARTED
23
Overall Study
COMPLETED
19
Overall Study
NOT COMPLETED
4

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Feasibility Study of the TruSculpt Radiofrequency Device

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
All Subjects
n=23 Participants
All subjects will receive 1 truSculpt radiofrequency treatment in desired area. TruSculpt: All subjects will receive 1 truSculpt radiofrequency treatment
Age, Categorical
<=18 years
0 Participants
n=99 Participants
Age, Categorical
Between 18 and 65 years
23 Participants
n=99 Participants
Age, Categorical
>=65 years
0 Participants
n=99 Participants
Sex: Female, Male
Female
19 Participants
n=99 Participants
Sex: Female, Male
Male
4 Participants
n=99 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=99 Participants
Race (NIH/OMB)
Asian
5 Participants
n=99 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
2 Participants
n=99 Participants
Race (NIH/OMB)
Black or African American
0 Participants
n=99 Participants
Race (NIH/OMB)
White
12 Participants
n=99 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=99 Participants
Race (NIH/OMB)
Unknown or Not Reported
4 Participants
n=99 Participants
Visible fat bulges, skin laxity, or cellulite
23 Participants
n=99 Participants

PRIMARY outcome

Timeframe: 12 weeks post-treatment

Degree of improvement in the treatment area at 12 weeks post-treatment compared with Baseline photo as assessed by the Investigator using Global Aesthetic Improvement Scale(GAIS): 4 = Very Significant Improvement (\>75%), 3 = Significant Improvement (51 - 75%), 2 = Moderate Improvement (26 - 50%), 1 = Mild Improvement (5 - 25%), or 0 = No Change (\<5%)

Outcome measures

Outcome measures
Measure
All Subjects
n=18 Participants
All subjects will receive 1 truSculpt radiofrequency treatment in desired area. TruSculpt: All subjects will receive 1 truSculpt radiofrequency treatment
Investigator Assessment of Improvement
0.67 score on a scale
Standard Deviation 0.47

Adverse Events

All Subjects

Serious events: 0 serious events
Other events: 23 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Other adverse events
Measure
All Subjects
n=23 participants at risk
All subjects will receive 1 truSculpt radiofrequency treatment in desired area. TruSculpt: All subjects will receive 1 truSculpt radiofrequency treatment
Skin and subcutaneous tissue disorders
Erythema
91.3%
21/23 • 12 weeks
Skin and subcutaneous tissue disorders
Edema
47.8%
11/23 • 12 weeks
Skin and subcutaneous tissue disorders
Nodules
60.9%
14/23 • 12 weeks
Skin and subcutaneous tissue disorders
Post treatment pain/discomfort
26.1%
6/23 • 12 weeks
Skin and subcutaneous tissue disorders
Purpura
17.4%
4/23 • 12 weeks

Additional Information

Margot Doucette

Cutera, Inc.

Phone: (415) 657-5518

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place