A Phase II Study of Weekly Genexol-PM in Patients With Hepatocelluar Carcinoma After Failure of Sorafenib
NCT03008512 · Status: TERMINATED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 5
Last updated 2021-02-04
Summary
This study evaluate activity and safety profile of weekly Genexol-PM in patients with advanced hepatocellular carcinoma for whom sorafenib treatment failed. Patients will receive Genexol-PM on days 1, 8, and 15 every 4 weeks.
Conditions
- Carcinoma, Hepatocellular
Interventions
- DRUG
-
Genexol-PM
Sponsors & Collaborators
-
Gachon University Gil Medical Center
lead OTHER
Principal Investigators
-
Dong Bok Shin, Professor · Gachon University Gil Medical Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 20 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-10-31
- Primary Completion
- 2021-02-28
- Completion
- 2021-02-28
Countries
- South Korea
Study Locations
More Related Trials
-
Sorafenib Monotherapy vs. TACE-sorafenib Sequential Therapy for HCC With Metastasis
NCT03518502 ·Status: UNKNOWN ·Phase: PHASE4
-
The Efficacy and Safety of HAIC With FOLFOX vs Sorafenib for Patients Who Showed TACE-resistant: a Retrospective Study
NCT05121571 ·Status: COMPLETED ·Phase: NA
-
Sorafenib Combined With Transarterial Chemoembolization in Treating HBV-infected Patients With Intermediate Hepatocellular Carcinoma
NCT01556815 ·Status: UNKNOWN ·Phase: PHASE2
-
Sorafenib as Adjuvant Treatment in the Prevention Of Recurrence of Hepatocellular Carcinoma (STORM)
NCT00692770 ·Status: COMPLETED ·Phase: PHASE3
-
Phase Ⅱ Study of HAIC of FOLFOX vs. Sorafenib in HCC Refractory to TACE
NCT03722498 ·Status: WITHDRAWN ·Phase: PHASE2
-
Systemic Chemotherapy Versus Transcatheter Arterial Chemoembolization(TACE) for Hepatocellular Carcinoma
NCT02585479 ·Status: WITHDRAWN ·Phase: PHASE2/PHASE3
-
Study of GC33 and Sorafenib in Combination in Advanced or Metastatic Liver Cancer (Hepatocellular Carcinoma)
NCT00976170 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy and Safety of Sorafenib (Nexavar) in Combination With Gemcitabine in Advanced Hepatocellular Carcinoma (HCC)
NCT00703365 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Estimate Safety and Efficacy of Sorafenib (BAY43-9006) in the Treatment of Hepatocellular Carcinoma
NCT00044512 ·Status: COMPLETED ·Phase: PHASE2
-
Analysis of the Role of Hepatocyte SLAMF3 Receptor and Drug Resistance Proteins (MDR) in Resistance to Treatment With Sorafenib in CHC Patients
NCT03113604 ·Status: WITHDRAWN
-
Study of TAC-101 as Second Line Treatment in Patients With Advanced Hepatocellular Carcinoma Who Received Sorafenib as First Line Therapy
NCT00687596 ·Status: TERMINATED ·Phase: PHASE2
-
Sorafenib VS TACE in HCC Patients With Portal Vein Invasion
NCT01480817 ·Status: TERMINATED ·Phase: PHASE2
-
Adjuvant Hepatic Arterial Infusional Chemotherapy After Curative Resection of Hepatocellular Carcinoma
NCT01088581 ·Status: COMPLETED ·Phase: PHASE3
-
Study of Sorafenib With Combination of Thalidomide in Hepatocellular Carcinoma (HCC)
NCT00971126 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Sorafenib Plus TACE Versus Sorafenib Alone as Postoperative Adjuvant Treatment for Resectable Primary Advanced HCC
NCT04143191 ·Status: UNKNOWN ·Phase: PHASE3
-
PM8002 in Combination With Chemotherapy as First Line Therapy in Hepatocellular Carcinoma
NCT05864105 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Study of Sorafenib and Infusional 5-Fluorouracil in Advanced Hepatocellular Carcinoma (HCC)
NCT00619541 ·Status: COMPLETED ·Phase: PHASE2
-
Sorafenib Alone Versus Sorafenib Combined With HAIC for Advanced HCC
NCT02774187 ·Status: COMPLETED ·Phase: PHASE3
-
A Randomized, Placebo-controlled, Double-blind Phase 2 Study With OSI-906 in Patients With Advanced HCC
NCT01101906 ·Status: TERMINATED ·Phase: PHASE2
-
A Study of PTX-9908 Injection for Non-resectable HCC with TACE
NCT03812874 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Correlation Between Sorafenib Plasma Concentrations, Toxicity and Disease Control Rate in Patients Treated by Sorafenib for Hepatocellular Carcinoma
NCT02834546 ·Status: COMPLETED
-
Sorafenib Tosylate and Chemoembolization in Treating Patients With Unresectable Liver Cancer
NCT01042041 ·Status: COMPLETED ·Phase: PHASE1
-
Randomized Phase II Trial of Chemoembolization and Sorafenib
NCT02908165 ·Status: WITHDRAWN ·Phase: PHASE2
-
Pembrolizumab in Advanced Hepatocellular Carcinoma as Second-line Treatment After Failure of Sorafenib
NCT03163992 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of the Effectiveness and Safety of AMG 386 and Sorafenib to Treat Advanced or Inoperable Hepatocellular Cancer
NCT00872014 ·Status: COMPLETED ·Phase: PHASE2