Repairing the Defect of Intervertebral Disc With Autologous BMSC and Gelatin Sponge After Microendoscopic Discectomy for Lumbar Disc Herniation
NCT03002207 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 25
Last updated 2024-12-27
Summary
In this prospective study the investigators seek to evaluate clinical outcomes after repairing the defect of intervertebral disc with autologous BMSC/gelatin sponge during microendoscopic discectomy for participants of lumbar disc herniation.
Conditions
- Lumbar Disc Herniation
Interventions
- DEVICE
-
Autologous Bone Marrow Stem Cell (BMSC)/gelatin sponge
Participants with lumbar disc herniation diseases are treated by Microendoscopic discectomy, and the defect of intervertebral disc is repaired with Autologous Bone Marrow Stem Cell (BMSC)/gelatin sponge after discectomy.
- PROCEDURE
-
The defect is sutured
Participants with lumbar disc herniation diseases are treated by Microendoscopic discectomy, and the defect is sutured after discectomy.
Sponsors & Collaborators
-
Zhanghao
lead OTHER
Principal Investigators
-
Xinlong Ma · Tianjin Hospital Of Tianjin
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-10-31
- Primary Completion
- 2024-12-20
- Completion
- 2024-12-22
Countries
- China
Study Locations
More Related Trials
-
SCLife®-LDD hUC-MSCs Injection Therapy for Patients With Lumbar Intervertebral Disc Degeneration
NCT06589271 ·Status: SUSPENDED ·Phase: PHASE1
-
The Safety/Efficacy Study of Human Umbilical Cord Mesenchymal Stem Cells Therapy (19#iSCLife®-LDP) for Lumbar Discogenic Pain
NCT04104412 ·Status: RECRUITING ·Phase: PHASE1
-
Autologous Adipose Tissue Derived Mesenchymal Stem Cells Transplantation in Patient With Lumbar Intervertebral Disc Degeneration
NCT01643681 ·Status: WITHDRAWN ·Phase: NA
-
Injection of Autologous Bone Marrow Aspirate in Patients With Degenerative Disc Disease.
NCT05146583 ·Status: UNKNOWN
-
Stem Cells vs. Steroids for Discogenic Back Pain
NCT04735185 ·Status: WITHDRAWN ·Phase: NA
-
Autologous, Culture-Expanded Mesenchymal Stromal Cells for Degenerative Disc Disease
NCT03461458 ·Status: TERMINATED ·Phase: PHASE1
-
Treatment of Degenerative Disc Disease With Allogenic Mesenchymal Stem Cells (MSV)
NCT01860417 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Lumbar Degenerative Disc Disease Treatment With Bone Marrow Autologous Mesenchymal Stem Cells (MSV)
NCT02440074 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
Autologous Adipose Derived Stem Cell Therapy for Intervertebral Disc Degeneration
NCT02338271 ·Status: UNKNOWN ·Phase: PHASE1
-
Restoration of Disc Height Reduces Chronic Low Back Pain
NCT00828880 ·Status: COMPLETED
-
The Comparative Study of Full-Endoscopic Cervical Posterior Discectomy and Anterior Cervical Decompression and Fusion
NCT04175535 ·Status: RECRUITING ·Phase: NA
-
Human Autograft Mesenchymal Stem Cell Mediated Stabilization of The Degenerative Lumbar Spine
NCT02529566 ·Status: UNKNOWN
-
Clinical Study on the Therapeutic Efficacy of Biportal Endoscopic Decompression Spine Surgery and Lumbar Decompression Fusion Surgery in the Treatment of Degenerative Lumbar Spondylolisthesis
NCT07289737 ·Status: RECRUITING
-
Effect of Duration of Symptoms on the Clinical and Functional Outcomes of Lumbar Microdiscectomy
NCT04538027 ·Status: COMPLETED ·Phase: NA
-
Study to Evaluate Safety and Effectiveness of Dynamic Stabilization Versus Lumbar Fusion in Treatment of Multilevel Lumbar Disc Degeneration Disease
NCT02385695 ·Status: UNKNOWN
-
Epidural Neuroplasty for the Treatment of Herniated Lumbar Disk
NCT03101033 ·Status: COMPLETED ·Phase: NA
-
Utilization of Autologous Mesenchymal Cells in Posterolateral Spinal Fusion in Degenerative Spine Disease
NCT03827096 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Safety and Efficacy Study of Matrilin-3 Pretreated Autologous Adipose Derived Mesenchymal Stem Cells Implantation in Chronic Low Back Pain Patients With Lumbar Intervertebral Disc Degeneration
NCT05011474 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Efficacy of Intradiscal Injection of Autologous BM-MSC in Worker Patients Affected by Chronic LBP Due to Multilevel IDD
NCT04759105 ·Status: COMPLETED ·Phase: PHASE2
-
The Influence of the Timing of Postoperative Rehabilitation Intervention on the Clinical Efficacy of Unilateral Biportal Endoscopic Spine System in the Treatment of Lumbar Disc Herniation
NCT07161232 ·Status: RECRUITING ·Phase: NA
-
Dispersal Pattern for Spine Injections (Gadolinium Contrast)
NCT02217280 ·Status: COMPLETED ·Phase: NA
-
Intervertebral DXM Gel Injection in Adults With Painful Lumbar Degenerative Disc Disease
NCT04727385 ·Status: UNKNOWN ·Phase: NA
-
A Pivotal Study of rhBMP-2/ACS/INTER FIX™ Device for Posterior Lumbar Interbody Fusion in Patients With Degenerative Disc Disease
NCT01491464 ·Status: TERMINATED ·Phase: NA
-
Percutaneous Transforaminal Endoscopic Discectomy vs Microendoscopic Discectomy for Treatment of Lumbar Disc Herniation
NCT01997086 ·Status: UNKNOWN ·Phase: PHASE4
-
Study Comparing Postoperative Treatment After Surgical Decompression for Lumbar Spinal Stenosis.
NCT05312281 ·Status: RECRUITING ·Phase: NA