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Collection and Measurement of Biomarkers in Prostate Cancer Radiotherapy Patients

NCT02997709 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 144

Last updated 2026-03-04

No results posted yet for this study

Summary

The purpose of this research study is to learn about: 1) How standard radiation treatment to prostate (primary radiotherapy) or the pelvis after prostatectomy (postoperative radiotherapy) may cause changes in MRI and PET imaging traits that might be used in the future to predict response. 2) Comparison of such MRI and PET imaging traits with the number of circulating tumor cells (CTCs) present in the blood prior to treatment and the changes in these counts after treatment. 3) How MRI and PET imaging characteristics and changes are related to the expression of genes in the cancer tissue obtained before treatment from prostate biopsy or a prior prostatectomy before treatment. 4) How the response of prostate cancer treatment relates to the imaging and CTC changes.

Conditions

Sponsors & Collaborators

  • Bankhead-Coley Florida Biomedical Research Program

    collaborator UNKNOWN

  • University of Miami

    lead OTHER

Principal Investigators

  • Alan Pollack, MD, PhD · University of Miami

Eligibility

Min Age
30 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-06-24
Primary Completion
2027-06-30
Completion
2032-06-30

Countries

  • United States

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02997709 on ClinicalTrials.gov