FLABRA: Frontline Approach for BRCA Testing in OC Treatment naïve Population. A LATIN AMERICA Epidemiologic Study
NCT02984423 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 471
Last updated 2020-07-10
Summary
This study aims to answer very important questions regarding the prevalence of somatic and germline mutations (sBRCAm and gBRCAm) in a population of newly diagnosed ovarian cancer patients from Latin America. These answers may be extremely helpful in the counseling for genetic risk and treatment approach in these populations and will aid in making treatment decisions in the future
Conditions
Sponsors & Collaborators
- lead INDUSTRY
Eligibility
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-12-27
- Primary Completion
- 2019-06-30
- Completion
- 2019-06-30
Countries
- Argentina
- Brazil
- Colombia
- Mexico
- Panama
- Peru
Study Locations
More Related Trials
-
Observational, Bi-directional (Prospective and Retrospective) Study for Patients With Newly Diagnosed Ovarian Cancer Stages IA to IVB, or Persistent or Recurrent Disease From January 2021; Irrespective of Histology
NCT07167433 ·Status: RECRUITING
-
Study to Assess Prevalence of BRCA1 and BRCA2 Mutation Among Ovarian, Primary Peritoneal and Fallopian Tube Cancer Patients in India
NCT03471572 ·Status: COMPLETED
-
Impact of Different BRCA1/2 Gene Variants on Response to Therapy and Prognosis of Ovarian Cancer
NCT06775470 ·Status: RECRUITING
-
Circulating Tumor DNA as an Early Marker of Recurrence and Treatment Efficacy in Ovarian Carcinoma
NCT03302884 ·Status: UNKNOWN ·Phase: NA
-
Olaparib Maintenance Monotherapy in Patients With BRCA Mutated Ovarian Cancer Following First Line Platinum Based Chemotherapy.
NCT01844986 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Olaparib Treatment in Relapsed Germline Breast Cancer Susceptibility Gene (BRCA) Mutated Ovarian Cancer Patients Who Have Progressed at Least 6 Months After Last Platinum Treatment and Have Received at Least 2 Prior Platinum Treatments
NCT02282020 ·Status: COMPLETED ·Phase: PHASE3
-
Olaparib, Durvalumab, and Tremelimumab in Treating Patients With Recurrent or Refractory Ovarian, Fallopian Tube or Primary Peritoneal Cancer With BRCA1 or BRCA2 Mutation
NCT02953457 ·Status: COMPLETED ·Phase: PHASE2
-
Search for Predictors of Therapeutic Response in Ovarian Carcinoma
NCT01391351 ·Status: COMPLETED ·Phase: NA
-
OVArian Cancer Non-Interventional Study - OVATAR
NCT02122588 ·Status: COMPLETED
-
A Study to Characterize the Outcomes of Olaparib Maintenance Monotherapy in Newly Diagnosed BRCAwt Ovarian Cancer
NCT05775549 ·Status: COMPLETED
-
Genomic BRCA and Extensive ovArian Cancer Testing
NCT04027868 ·Status: COMPLETED
-
Olaparib Real-world Utilization and Clinical Outcomes in France, Italy, and the UK
NCT04532645 ·Status: COMPLETED
-
Mirvetuximab Soravtansine (IMGN853), in Folate Receptor Alpha (FRα) High Recurrent Ovarian Cancer
NCT04274426 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
China Ovarian Cancer BRCA Testing Study
NCT03203993 ·Status: TERMINATED
-
Mirvetuximab Soravtansine (MIRV) With Carboplatin in Second-line Treatment of Folate Receptor Alpha (FRα) Expressing, Platinum-sensitive Epithelial Ovarian Cancer
NCT05456685 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Breast Cancer After Ovarian Cancer During and/or After Therapy: Genomic Evaluation
NCT05763472 ·Status: UNKNOWN
-
Prospective Identification and Validation of "BRCANess" Profile in Ovarian Epithelial Cancer
NCT02524808 ·Status: UNKNOWN
-
Oregovomab in Combination With Bevacizumab Plus Chemo in BRCA Wild Type Platinum Sensitive Recurrent Ovarian Cancer
NCT04938583 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Study of Mirvetuximab Soravtansine in Combination With Bevacizumab, Carboplatin, Pegylated Liposomal Doxorubicin, Pembrolizumab, or Bevacizumab + Carboplatin in Participants With Folate Receptor Alpha (FRα) Positive Advanced Epithelial Ovarian Cancer, Primary Peritoneal, or Fallopian Tube Cancer
NCT02606305 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Olaparib in Patients With Recurrent Ovarian Cancer Wild Type for Germline and Somatic BRCA 1 and 2 Genes: The MITO 31 Translational Study
NCT04091204 ·Status: UNKNOWN ·Phase: PHASE2
-
BRCA 1/2 Mutation in Korean Patients With Epithelial Ovarian Cancer
NCT02963688 ·Status: COMPLETED
-
Assessment of Efficacy of AZD2281 in Platinum Sensitive Relapsed Serous Ovarian Cancer
NCT00753545 ·Status: COMPLETED ·Phase: PHASE2
-
AZD5335 vs. Mirvetuximab Soravtansine in FRα-high and AZD5335 vs. Chemotherapy in FRα-low Platinum-resistant Ovarian Cancer
NCT07218809 ·Status: RECRUITING ·Phase: PHASE3
-
Saracatinib and Paclitaxel in Platinum-resistant Ovarian Cancer
NCT01196741 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
PARP-inhibition and CTLA-4 Blockade in BRCA-deficient Ovarian Cancer
NCT02571725 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2