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Mussel Intake and Vitamin D Status in Humans

NCT02982525 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2019-10-09

No results posted yet for this study

Summary

A significant proportion of the United Kingdom population have inadequate levels of vitamin D in their blood. Vitamin D is a fat-soluble vitamin that is essential for the growth and maintenance of healthy bones through increasing dietary calcium absorption within the body. A low vitamin D status has also been associated with other diseases such as osteoporosis, cancer (especially colorectal cancer), cardiovascular disease and type 1 diabetes. Our skin is able to synthesise vitamin D upon exposure to sunlight in summer. If exposure to sunlight is limited, then a dietary supply of vitamin D becomes essential.

However, very few foods contain vitamin D. Among the best dietary sources of vitamin D are oily fish (including salmon, mackerel, herring and trout) and fish oils. Recently, the investigators found that certain shellfish, especially mussels, contain significant amounts of a metabolite of vitamin D, 25(OH)D3. Consumption of this metabolite, as a supplement, has already been shown to improve vitamin D status in humans. Whether consumption of mussels improves vitamin D status is unknown.

In this study the investigators will be looking at whether consumption of 1, 2 or 3 portions of mussels per week for 12 weeks increases vitamin D status in healthy people.

Conditions

Interventions

DIETARY_SUPPLEMENT

No Mussels

Habitual diet only

DIETARY_SUPPLEMENT

One mussel portion

1 x 75g mussel portions provided per week

DIETARY_SUPPLEMENT

Two mussel portions

2 x 75g mussel portions provided per week

DIETARY_SUPPLEMENT

Three mussel portions

3 x 75g mussel portions provided per week

Sponsors & Collaborators

  • University of Aberdeen

    lead OTHER

Principal Investigators

  • Baukje De Roos, PhD · University of Aberdeen, The Rowett Institute

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-11-28
Primary Completion
2017-04-20
Completion
2018-12-31

Countries

  • United Kingdom

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02982525 on ClinicalTrials.gov