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Iron Long-Term Labelling Study Malawi

NCT02977806 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 48

Last updated 2019-04-02

No results posted yet for this study

Summary

Conventional indirect indicators of iron status, using serum and red blood cell biomarkers, are confounded by inflammation from common infections in sub-Saharan Africa, a region with a high prevalence of iron deficiency, making the assessment of iron balance and efficiency of iron intervention difficult. A new method allowing accurate measurement of long-term oral iron absorption and allowing the estimation of iron requirements is highly needed. Such a novel method to quantify iron absorption and requirements using isotope dilution measurements in children should be validated in the present prospective observational study by following-up a group of 49 children given a stable iron isotope in an earlier trial. We will request seven blood samples within 2 years (sampling every four months) from the participants which will allow us to measure isotopic dilution for estimating total oral iron absorption over these 24 months.

Conditions

  • Iron Absorption

Sponsors & Collaborators

  • Prof. Michael B. Zimmermann

    lead OTHER

Principal Investigators

  • Michael Zimmermann, Prof. · Human Nutrition Laboratory, ETH Zürich

Eligibility

Min Age
3 Years
Max Age
10 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-03-27
Primary Completion
2019-03-15
Completion
2019-12-31

Countries

  • Malawi

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02977806 on ClinicalTrials.gov