Non-interventional Study of Kyprolis® in Combination With Revlimid® and Dexamethasone or Dexamethasone Alone or in Combination With Darzalex® and Dexamethasone in Multiple Myeloma Patients
NCT02970747 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 359
Last updated 2025-11-25
Summary
The objective of this non-interventional study (NIS) is to evaluate patients' adherence and persistence to carfilzomib therapy in combination with lenalidomide and dexamethasone or in combination with dexamethasone alone or in combination with daratumumab and dexamethasone in adult patients with multiple myeloma (MM) who have received at least one prior therapy in a real-life setting.
Conditions
- Multiple Myeloma in Relapse
Interventions
- DRUG
-
In accordance with SmPC.
Sponsors & Collaborators
- collaborator INDUSTRY
-
iOMEDICO AG
lead INDUSTRY
Principal Investigators
-
Wolfgang Knauf, Professor · Centrum für Hämatologie und Onkologie Bethanien, Germany, 60389 Frankfurt a.M.
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-10-25
- Primary Completion
- 2025-04-26
- Completion
- 2025-04-26
Countries
- Germany
Study Locations
More Related Trials
-
Phase 1b Multicenter Study of Carfilzomib With Lenalidomide and Dexamethasone in Relapsed Multiple Myeloma
NCT00603447 ·Status: COMPLETED ·Phase: PHASE1
-
Phase II Study of Carfilzomib, Pomalidomide, and Dexamethasone for Myeloma Patients Who Had Relapsed or Progressed After Carfilzomib, Lenalidomide, and Dexamethasone
NCT05509374 ·Status: UNKNOWN ·Phase: PHASE2
-
S1304, Carfilzomib and Dexamethasone for Treating Patients With Relapsed or Refractory Myeloma
NCT01903811 ·Status: COMPLETED ·Phase: PHASE2
-
Weekly 70 mg/m2 Carfilzomib for Multiple Myeloma Patients Refractory to 27 mg/m2 Carfilzomib
NCT02294357 ·Status: TERMINATED ·Phase: PHASE2
-
Study of the Combination of Panobinostat & Carfilzomib in Patients With Relapsed &/or Refractory Multiple Myeloma
NCT01549431 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Carfilzomib Plus Dexamethasone in Adults With Relapsed or Refractory Multiple Myeloma at US Community Oncology Centers
NCT03512353 ·Status: TERMINATED ·Phase: PHASE2
-
Carfilzomib and Lenalidomide With Dexamethasone Combination in Newly Diagnosed, Previously Untreated Multiple Myeloma
NCT01029054 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Carfilzomib in Combination for the Treatment of RR MM
NCT04004338 ·Status: UNKNOWN
-
High-Dose Weekly Carfilzomib Plus Cyclophosphamide and Dexamethasone in the Treatment of Relapsed Multiple Myeloma
NCT02597062 ·Status: COMPLETED ·Phase: PHASE2
-
A Study Comparing Once-weekly vs Twice-weekly Carfilzomib in Combination With Lenalidomide and Dexamethasone in Subjects With Relapsed or Refractory Multiple Myeloma
NCT03859427 ·Status: COMPLETED ·Phase: PHASE3
-
Carfilzomib, Lenalidomide, and Dexamethasone Versus Bortezomib, Lenalidomide and Dexamethasone (KRd vs. VRd) in Patients With Newly Diagnosed Multiple Myeloma (COBRA)
NCT03729804 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Study of Carfilzomib, Daratumumab and Dexamethasone for Patients With Relapsed and/or Refractory Multiple Myeloma.
NCT03158688 ·Status: COMPLETED ·Phase: PHASE3
-
High Dose Carfilzomib for Newly Diagnosed Myeloma
NCT02937571 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Dose Escalation Study of the Combination of Lenalidomide (Revlimid®), Dexamethasone and Cyclophosphamide in Patients Refractory or Relapsing From Stable Disease With Multiple Myeloma
NCT00915408 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Carfilzomib, Lenalidomide, and Dexamethasone in New Multiple Myeloma Patients
NCT01402284 ·Status: COMPLETED ·Phase: PHASE2
-
Carfilzomib, Cyclophosphamide, Dexamethasone in Multiple Myeloma
NCT03336073 ·Status: UNKNOWN ·Phase: PHASE2
-
Carfilzomib Thalidomide and Dexamethasone in Patients With Relapsed and/or Refractory Multiple Myeloma
NCT03140943 ·Status: UNKNOWN ·Phase: PHASE2
-
Carfilzomib in Combination With Dexamethasone (Kd) in Chinese Patients With Relapsed & Refractory Multiple Myeloma
NCT03029234 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Evaluate Dara-CyBorD in Previously Untreated and Relapsed Subjects With Multiple Myeloma
NCT02951819 ·Status: COMPLETED ·Phase: PHASE2
-
Dexamethasone, Carfilzomib, & Nivolumab With Pelareorep for Relapsed/Refractory Multiple Myeloma
NCT03605719 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Initial Treatment With Elotuzumab, Carfilzomib, Lenalidomide and Dexamethasone in Multiple Myeloma
NCT02969837 ·Status: COMPLETED ·Phase: PHASE2
-
Panobinostat and Carfilzomib in Treating Participants With Relapsed or Refractory Multiple Myeloma
NCT01301807 ·Status: COMPLETED ·Phase: PHASE1
-
Wild-Type Reovirus in Combination With Carfilzomib and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma
NCT02101944 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Weekly Carfilzomib in Combination With Dexamethasone for Progressive Multiple Myeloma
NCT01677858 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Carfilzomib, Pegylated Liposomal Doxorubicin Hydrochloride, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma
NCT01246063 ·Status: COMPLETED ·Phase: PHASE1/PHASE2