The Effects of Apomorphine on Experimental and Clinical Pain in Patients With Chronic Radicular Pain
NCT02969629 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 59
Last updated 2016-11-22
Summary
The study aimed to explore the effect of the dopamine agonist apomorphine on spontaneous pain intensity and evoked cold clinical and experimental pain in patients with lumbar radicular neuropathic pain (NP). Patients received either apomorphine or placebo in a randomized double-blinded manner.
Conditions
- Chronic Low Back Pain
Interventions
- DRUG
-
Apomorphine
- DRUG
-
Normal Saline
Sponsors & Collaborators
-
Rambam Health Care Campus
lead OTHER
Principal Investigators
-
Elon Eisenberg, MD · Rambam Health Care Campus
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- TRIPLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2012-12-31
- Primary Completion
- 2014-12-31
- Completion
- 2014-12-31
Countries
- Israel
Study Locations
More Related Trials
-
Effect of NRD135S.E1 in Peripheral Neuropathic Pain in Diabetic Patients
NCT02345291 ·Status: COMPLETED ·Phase: PHASE2
-
A Study Comparing the Efficacy and Safety of ABT-652 to Placebo in Subjects With Diabetic Neuropathic Pain
NCT01579279 ·Status: TERMINATED ·Phase: PHASE2
-
Effect of Milnacipran in Chronic Neuropathic Low Back Pain
NCT01225068 ·Status: COMPLETED ·Phase: PHASE2
-
A Single Dose Pharmaco-Diagnostic for Peripheral Nerve Continuity After Trauma
NCT04026568 ·Status: TERMINATED ·Phase: PHASE2/PHASE3
-
Pretreatment Identification of Duloxetine Success in Neuropathic Pain Patients
NCT01363284 ·Status: COMPLETED ·Phase: NA
-
Efficacy and Safety of Ralfinamide in Patients With Chronic Neuropathic Low Back Pain
NCT01019824 ·Status: COMPLETED ·Phase: PHASE3
-
Intrathecal Therapy for Chronic Non-Cancer Pain: An Analysis of Its Efficacy
NCT01564069 ·Status: COMPLETED
-
Analgecine for Treatment of Low Back Pain
NCT02168010 ·Status: COMPLETED ·Phase: PHASE3
-
Central Pain Study for ABX-1431
NCT03138421 ·Status: COMPLETED ·Phase: PHASE1
-
Neurotropin to Treat Chronic Neuropathic Pain
NCT00006289 ·Status: TERMINATED ·Phase: PHASE2
-
Chronic Pain in Spinal Cord Injury
NCT00006428 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy and Safety of EN3324 (Axomadol) in Subjects With Chronic Low Back Pain
NCT01043263 ·Status: COMPLETED ·Phase: PHASE2
-
A Proof of Concept Study to Investigate the Effect of a New Treatment in Patient With Chronic Pain
NCT02459197 ·Status: COMPLETED ·Phase: NA
-
A Multicenter Study Comparing the Analgesic Effects and Safety of ABT-639 Compared to Placebo in Subjects With Diabetic Neuropathic Pain
NCT01345045 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis
NCT06071949 ·Status: UNKNOWN ·Phase: PHASE3
-
A Study to Investigate the Effects of a New Treatment in Patients With Chronic Pain
NCT02301169 ·Status: COMPLETED ·Phase: NA
-
Chronic Pain After Amputation
NCT00006427 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy and Tolerability of AP707 in Patients With Chronic Back Pain
NCT06072560 ·Status: UNKNOWN ·Phase: PHASE3
-
Efficacy and Tolerability of Novel A2A Agonist in Treatment of Diabetic Neuropathic Pain
NCT00452777 ·Status: COMPLETED ·Phase: PHASE2
-
Chronic Pain Master Protocol (CPMP): A Study of LY3016859 in Participants With Chronic Low Back Pain
NCT04529096 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of the Safety, Tolerability and Pharmacokinetics of MEDI0618 in Healthy Volunteers
NCT04198558 ·Status: COMPLETED ·Phase: PHASE1
-
A Pilot Trial of Intravenous (IV) Pamidronate for Low Back Pain
NCT00101790 ·Status: UNKNOWN ·Phase: PHASE1
-
A Study to Evaluate the Safety and Tolerability of Arbaclofen Placarbil (XP19986) in Subjects With Acute Back Spasms
NCT00817986 ·Status: COMPLETED ·Phase: PHASE2
-
Discovery and Analytical Validation of Inflammatory Bio-signatures of the Human Pain Experience
NCT05074485 ·Status: RECRUITING ·Phase: PHASE1
-
Omnitram Safety and Efficacy in the Treatment of Diabetic Neuropathy
NCT03664921 ·Status: COMPLETED ·Phase: PHASE2