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RCT of TAE Simultaneously Combined Thermal Ablation for Large Hepatocellular Carcinoma

NCT02964260 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 410

Last updated 2021-05-14

No results posted yet for this study

Summary

This study intends to evaluate the efficacy and safety of Transarterial embolization (TAE) simultaneously combined with thermal ablation for large hepatocellular carcinoma (HCC). Half participants will receive TAE simultaneously combined with thermal ablation and the other half receive TACE sequentially combined with thermal ablation, which is a conventional treatment for HCC patients.

Conditions

  • Hepatocellular Carcinoma, Adult

Interventions

DRUG

Chemotherapy drug

Doxorubicin/Platinum agents

DRUG

Embolic agents

Lipiodol/Gelatin sponge/PVA/Blank microspheres

PROCEDURE

Simultaneously

1-3 days

PROCEDURE

Sequentially

1 month

DEVICE

Ablation

Radiofrequency ablation/Microwave ablation

Sponsors & Collaborators

  • First Affiliated Hospital, Sun Yat-Sen University

    collaborator OTHER

  • Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

    collaborator OTHER

  • Third Affiliated Hospital, Sun Yat-Sen University

    collaborator OTHER

  • Sixth Affiliated Hospital, Sun Yat-sen University

    collaborator OTHER

  • Guangdong Provincial People's Hospital

    collaborator OTHER

  • Sun Yat-sen University

    lead OTHER

Principal Investigators

  • Jinhua Huang, Ph.D · Sun Yat-sen University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-05-31
Primary Completion
2022-12-31
Completion
2022-12-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02964260 on ClinicalTrials.gov