A Prospective Cohort Study on Drug-induced Liver Injury in China（DILI-P）

Summary

This is a multi-center, prospective, non-interventional cohort study .

Its primary objectives are:

1. assess DILI patients' clinical characteristics, disease progression and influencing factors in clinical practice;
2. learn about suspected drug caused DILI,rechallenging, liver biochemical abnormalities mode, etc.

Conditions

• Drug-induced Liver Injury

Sponsors & Collaborators

• Drug Induced Liver Disease Study Group

  lead OTHER

Principal Investigators

• Yimin Mao · RenJi Hospital

• Chengwei Chen · No.85 Hospital of PLA

• Xingfang Li · Pulmonary Hospital of Lanzhou

• Yiling Li · First Hospital of China Medical University

• Dongliang Li · Fuzhou General Hospital

• Suocai Zhang · Changzhou Third People 's Hospital

• Rongxia Sang · First Hospital of Shijiazhuang City

• Zhihui Li · Hebei Chest Hospital

• Feng Sun · First Affiliated Hospital of Heilongjiang Chinese Medicine University

• Wushu Yan · Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

• Yanqin Wu · Bazhou People 's Hospital

• Xu Lian · Mudanjiang Red Flag Hospital

• Mingfang Wang · Pingdingshan People's Hospital No.1

• Yanrong Shi · General Hospital of Pingdingshan Coal Industry Company

• Hongwei Chen · Luoyang Central Hospital

• Ximei Wang · Third Hospital Affiliated to Henan University of Science and Technology

• Hongling Liu · The First People's Hospital of Luoyang

• Renping Li · The Second Hospital Affiliated to Henan University of Science and Technology

• Zhengsheng Zou · Beijing 302 Hospital

• Jiguang Ding · The Third Affiliated Hospital of Wenzhou Medical University

• Yanjun Guo · Daqing oilfield general hospital

• Weixin He · The No.123 Hospital of Chinese People's Liberation Army

• Wufang Qi · Tianjin First Central Hospital

• Yuqin Xu · The No.211 Hospital of Chinese People's Liberation Army

• Jing Zhang · Beijin Youan Hospital,Capital Medical University

• Peilan Zong · Jiangxi Chest Hospital

• Yuefei Shen · The First People's Hospital of Hangzhou Xiaoshan District

• Chunyan Zhou · Infectious Diseases Hospital of Shangqiu

• Baijing Ding · The Second People's Hospital of Wuhu

• Liyun Chen · Wuhu Third People's Hospital

• Yongze Guo · Affiliated Hospital of Hebei University of Engineering

• Haibin Wang · Fifth Hospital of Shijiazhuang City

• Hui Guo · First Teaching Hospital of Tianjin University of Traditional Chinese Medicine

• Hongling Liu · Beijing 302 Hospital

• Yingjian Zhang · The First Affiliated Hospital of Henan University of Science and Technology

• Qing Mao · Southwest Hospital, China

• Liaoyun Zhang · The First Affiliated Hospital of Shanxi Medical University

• Jiawei Gen · First People's Hospital of Yunnan Province

• Weize Zuo · The First Affiliated Hospital of Medical College,Shihezi University

• Xia Zhang · Nanjing Chest Hospital

• Xuan Zhu · The First Affiliated Hospital of Nanchang University

• Feng Shuai · Linyi People's Hospital

• Kunyun Yang · Hunan Chest Hospital

• Chuanwu Zhu · The Fifth People,Hospital of Suzhou

• Wei Ge · Renmin Hospital of Wuhan University

• Xiaojin Wang · 85 Hospital of People's Liberation Army

• Jiajun Liu · The First Affiliated Hospital of Xiamen University

• Yan Huang · Xiangya Hospital of Central South University

• Fangping He · First Affiliated Hospital of Xinjiang Medical University

• Xinmin Zhou · Xijing Hospital

• Aiqing Lin · The First Affiliated Hospital of Inner Mongolia University of Science and Technology

• Xiaojing Jiang · Wuhan General Hospital of Guangzhou Military

• Qing Xie · Ruijin Hospital

• Qingge Zhang · Xingtai People's Hospital

• Yanyan Yu · Peking University First Hospital

• Jing Yuan · Shenzhen Third People's Hospital

• Shiwu Ma · Kunming General Hospital of Chengdu Military Area Command

• Jun Chen · Second Xiangya Hospital of Central South University

• Qinghua Yao · Zhejiang Cancer Hospital

• Yihong Zhang · The No.457 Hospital of Chinese People's Liberation Army

• Qi Wang · Second Hospital of Shanxi Medical University

• Xiaozhong Wang · Xinjiang Autonomous Region Hospital of TCM

• Yongwen Ma · Daqing Longnan Hopital

• Fangfang Lv · Sir Run Run Shaw Hospital

• Xiaojun Zhang · Ankang City Central Hospital

• Riwang Hu · The Fouth People's Hospital of Datong

• Yi Song · Chongqing Traditional Chinese Medicine Hospital

• Peng Hu · The Second Affiliated Hospital of Chongqing Medical University

• Wen Xie · Beijing Ditan Hospital

• Yongguo Li · First Affiliated Hospital of Harbin Medical University

• Haiyan Jin · Yanbian University Hospital

• Zheng Li · The First People's Hospital of Qinzhou

• Shuixiang He · First Affiliated Hospital Xi'an Jiaotong University

• Lei Li · Anhui Provincial Hospital

• Junqi Niu · The First Affiliated Hospital of Jilin University

• Bin Jiang · The Second People's Hospital of Liaoyuan

• Jing You · First Affiliated Hospital of Kunming Medical University

• Youqin Yan · WUHAN NO.7 HOSPITAL

• Lvye Xv · General Hospital of The Yangtze River Shipping

• Changyong Zhang · Wuhan Mental Health Centre

• Guanghua Xv · Ya'nan University Affiliated Hospital

• Hongbin Li · The First Affiliated Hospital of Anhui Medical University

• Yongfeng Yang · The Second Hospital of Nanjing Medical University

• Xilian Dong · Yuncheng Central Hospital

• Xuefeng Su · LinFen People's Hospital

• Mudan Yang · Shaanxi Provincial Cancer Hospital

• Zhen Ma · The Affiliated Hospital of Inner Mongolia Medical University

• Hong Tang · West China Hospital

• Chenghai Liu · Shanghai Shuguang Hospital

• Zhenyu Yan · South China University of Science And Technology Affiliated Hospital

• Fei Qiao · Jiangsu province hospital of TCM

• Xingxiang Yang · Sichuan Province Hospital

• Jinjun Chen · Nanfang Hospital, Southern Medical University

• Weihong Sha · Guangdong Provincial People's Hospital

• Jie Jin · First People's Hospital of Hangzhou

• Feng Lin · Hainan General Hospital

• Guoqi Zheng · Cangzhou Central Hospital

• Jiyao Wang · Zhong Shan Hospital

• Lin Chen · LanZhou University

• Dongliang Yang · Tongji Medical College of Huazhong University of Science and Technology

• Li Chen · The Center Hospital Of Maanshan

• Guizhou Zou · The Second Hospital of Anhui Medical University

• Yong Wang · Fuyang First People's Hospital

• Lianqing Lou · Yiwu Central Hospital

• Huaming Li · The Third People's Hospital of Hangzhou

• Shifang Chen · Huzhou Central Hospital

• Zhifen Pan · Affiliated Hospital of Jiaxing University

• Wenlong Zheng · Hangzhou Hospital of Traditional Chinese Medicine

• Jingbo Pei · Hangzhou Xiaoshan Hospital of Traditional Chinese Medicine

• Feng Guo · Hangzhou Xiaoshan First People's Hospital

• Feng Qian · Dongyang People's Hospital

• Jianzheng Mao · Zhejiang Quhua Hospital

• Ahuo Ma · Shaoxing People's Hospital

• Qinhong Zheng · People's Hospital of Quzhou

• Jufen Xu · Tongxiang First People's Hospital

• Jiemin Hong · Ningbo Yinzhou No.2 Hospital

• Jianwei Shen · Ningbo Medical Center Lihuili Eastern Hospital

• Yunsong Qian · Ningbo No.2 Hospital

• Weihong Du · Jinhua Central Hospital

• Jiaxin Liu · Huzhou Hospital of Traditional Chinese Medicine

• Qingjing Ru · Zhejiang Construction Hospital

• Chunsheng Zhao · The No.98 Hospital of Chinese People's Liberation Army

• Yinxia Hao · Baoding First Central Hospital

• Li Sun · Xi'an No.3 Hospital

• Wenlei Hu · Le Qin People's Hospital

• Shuangsuo Dang · Second Affiliated Hospital of Xi'an Jiaotong University

• Yu Chen · Zhengzhou No.6 People's Hospital

• Zhaoxia Liu · First Affiliated Hospital of Heilongjiang Chinese Medicine University

• Yang Pan · Heilongjiang Provincial Hospital of Traditional Chinese Medicine

• Yi Shen · Dandong City Infectious Disease Hospital

• Xia Li · Baoding City Infectious Disease Hospital

• Qian Zhong · Anshan Central Hospita

• Zhixiong Fang · Xiangtan Central Hospita

• Xiaoping Xu · Xiangxi Autonomous Prefecture People's Hospital

• Sihai Li · The First People's Hospital of YueYang

• Hui Tian · The People's Hospital of Xuancheng City

• Shiquan Ka · The First People's Hospital of Lanzhou City

• Dongfang Li · Anhui Province Chest Hospital

• Yuqiang Nie · Guangzhou First People's Hospital

• Yan Song · Heilongjiang Mudanjiang Nanshan Hospital

• Xiaoyan Guo · Second Affiliated Hospital of Xi'an Jiaotong University

• Caiyan Zhao · Hebei Medical University Third Hospital

• Yuemin Nan · Hebei Medical University Third Hospital

• Dingguo Wang · People 's Hospital of Kaizhou District, Chongqing City

• Li Wang · Public Health Clinical Center of Chengdu

• Lixin Tong · First Hospital of Hebei Medical University

• Hao Wu · West China Hospital,Huaxi University

• Shurui Piao · Jinshan Hospital Fudan University

• Lvfeng Yao · Meng Chao Liver and Gallbladder Hospital of Fujian Medical University

• Yanqing Tian · Affiliated Hospital of Hebei University

• Zhenbin Hu · The First Affiliated Hospital of Guangxi University of Chinese Medicine

• Caisheng Wang · No.2 Hospital Of Huhhot

• Xiaoyan Wang · The Third Xiangya Hospital of Central South University

• Feng Jin · Shandong Provincial Chest Hospital

• Yanbo Jiang · Donggang Center Hospital

• Zhiqiang Wang · The 3Th People's Hospital Of Hengshui

• Yu Xiong · Shandong Provincial Chest Hospital

• Xinmei Guo · Shandong Provincial Chest Hospital

• Yan Zhuang · People's Hospital Of Nongan county

• Chaoren Zhao · Shandong Provincial Chest Hospital

• Zhonghua Zhao · Tuberculosis Department, Shandong Provincialchest Hospital

• Meiying Lin · Tuberculosis Department, Shandong Provincialchest Hospital

• Jihong Yang · Affiliated Hospital of Hebei University

• Jingyi Zhang · The Center Hospital Of Maanshan

• Sangen Chen · People's Hospital Of Jinxian county

• Yongping Pan · The Fourth Affiliated Hospital of Nanchang University

• Ruipu Li · Second Central Hospital of Baoding

• Xueshan Tao · Lushan Tuberculosis Prevention and Control Hospital

• Shilin Qu · Ganzhou People's Hospital

• Jie Liu · Jingzhou Chest Hospital

• Diefeng Yin · People's Hospital Of Luxi county

• Jianfeng Wu · Chinese Medicine Hospital of Gao'an City

• Xueqiang Jiang · Sinopharm Dongfeng General Hospital

• Jianwei Yang · Fujian Cancer Hospital

• Yong Yang · The 94th Hospital of the People's Liberation Army

• Chengyun Yang · People's Hospital Of Nanchang county

• Shengjun Li · People's Hospital Of Xunyang

• Jizhu Zhang · The Third People's Hospital Of Weifang

• Jianjun Zhao · The Third People's Hospital Of Weifang

• Gang Wu · The Third People's Hospital Of Jiujiang City

• Yong Li · Fengyang County People's Hospital

• Yansheng Sun · Infectious Disease Hospital Of Heilongjiang Province

• Xiong Tang · Third People's Hospital Of Jiujiang City

• Shousong Zhao · The First Affiliated Hospital of Bengbu Medical University

• Jiandao Zhang · Lingbi County People's Hospital

• Long Yu · Liu'an People's Hospital

• Weihua Xun · Shexian People's Hospital

• Yong Jia · Anhui Provincial Hospital

• Yi Li · Anhui Provincial Hospital Infectious Hospital

• Zhengmao Yang · The Second People's Hospital Of Lanzhou City

• Jianmin Liu · Zhuzhou No.2 Hospital

• Huafa Yin · The First Affiliated Hospital of Anhui Medical University

• Meilong Ding · Anhui Province Xuancheng City Central Hospital

• Shanlou Hu · People's Hospital Of Dongzhi county

• Yi Ding · Xiaoxian People's Hospital

• Weidong Fang · Huangshan City People's Hospital

• Liu Hong · Anhui Wuhu County Hospital

• Xiaorong Xu · Bozhou Hospital of Traditional Chinese Medicine

• Delian Wu · Suzhou Hospital Affiliated To Anhui Medical University

• Yong Huang · The Second People's Hospital of Hefei

• Qiliang Tan · Dazhou Central Hospital

• Songqing Liao · Huainanchaoyang Hospital

• Bin Yao · The People's Hospital Huaibei

• Shuiqing Jiang · Huainan First People's Hospital

• Yanmin Wang · Infectious Disease Hospital Of Baishan

• Lei Zhang · Anhui Chest Hospital

• Wenhong Lin · Anhui Chest Hospital

• Wengang Zhang · Tonghua Central Hospital

• Chongfeng Gu · The Ninth People's Hospital Of Jilin

• Zhe Zhang · Jilin Tuberculosis Prevention and Control Institute

• Junfeng Wang · Jixijikuang Hospital

• Jie Zhou · Tianjin Tuberculosis Prevention and Control Center

• Guomin Tang · Renmin Hospital Of Shayang

• Zhuo Li · Baiyupao Hospital

• Guohui Zhu · The Third People's Hospital Of Weifang

• Xingping Liu · The Third People's Hospital Of Weifang

• Jingen Wang · Zhangshu People's Hospital

• Xinyan Zhao · Beijing Friendship Hospital

• Hongliang Liang · Avic 363 Hospital

• Lijun Liu · Yiyang Central Hospital

• Fangchun Li · Fengcheng People's Hospital

• Jianwei Zhou · Xiangdong Hospital Hunan Normal University

• Zhongrui Su · Zhangjiajie City People's Hospital

• Wei Xiao · The Third Xiangya Hospital of Central South University

• Bohui Yuan · Qitaihe Coal Mine Hospital

• Chun Yang · Beilun People's Hospital

• Gaizhi Zhang · Luohe Psychiatric Hospital

• Ming Li · No.2 People's Hospital of Fuyang City

• Zhixue Zhang · Qiqihar Tuberculosis Prevention and Control Center

• Wei Yue · The First People's Hospital of Yunnan

• Li Zhou · Ningbo Medical Center Lihuili Eastern Hospital

• Xiaoqing Li · Anqing Municipal Hospitalis

• Chunge Tian · Dengzhou Central Hospital

• Tianming Wang · No.1 People's Hospital Of Zhumadian

• Ji'ao Han · People's Hospital of Zhengzhou University

• Jingxia Ma · People's Hospital Of Xinye

• Jie Bao · The First People's Hospital of Xinmi

• Jianhui Sun · Weihui People's Hospital

• Xiaoju Luo · Yuanyang Central Hospital

• Weili Niu · The Third People's Hospital Of Hebi

• Ming Wang · Hepatobiliary Hospital Of Jilin

• Yiwen Qiao · Dengzhou Hospital of TCM

• Chuan Zhao · Suining Infectious Diseases Hospital

• Xiaoqian Zhang · Anhui Mental Health Center

• Jingchao Guo · Wugang People's Hospital

• Weihua Liu · General Hospital of Heilongjiang Provincial Agricultural Reclamation Bureau

• Feng Wu · Baoji People's Hospital

• Man Chen · Taian Enliang Hospital

• Hong Wu · Xiuyan Central Hospital

• Shansong Bai · Anshan Mental Health Center

• Xiuying Men · General Hospital Of Liaohe Oilfield

• Yanhua Jiang · Tiefa Coal Group General Hospital

• Junzu Yang · The People's Hospital Of Lingchengqu

• Haiyan Zhou · Baoshan Hospital Of Chifeng

• Yu Feng · The Third Affiliated Hospital of Jinzhou Medical University

• Yihua Song · Liaoyang City Central Hospital

• Tao Yang · Panshan Mental Rehabilitation Hospital

• Yueping Li · Wafangdian Central hospital

• Guosheng Jiang · People's Hospital Of Ningjinxian

• Bo Zhang · Taian City Central Hospital

• Shujun Geng · Hebei Chest Hospital

• Jin Huang · The Second People's Hospital Of Changzhou

• Fengming Yin · The 169th Hospital Of P.L.A.

• Weiguo He · Public Health Affiliated Hospital,University Of South China

• Zhefeng Zhong · Affiliated Nanhua Hospital，University Of South China

• Yuan Yang · First Affiliated Hospital Xi'an Jiaotong University

• Guoping Fang · The Third People's Hospital Of Changzhou

• Qiang Miao · Tonghua Tuberculosis Prevention and Control Center

• Xin'guang Huang · The Fourth People's Hospital of Chenzhou

• Duanbao Tian · The Fourth People's Hospital Of Zibo

• Yaoming Yuan · People's Hospital Of Shishou

• Yuzi Lin · Yanji Tuberculosis Prevention and Control Center

• Ligang Chen · Dunhua Tuberculosis Prevention and Control Center

• Yu Zhang · Huichun Tuberculosis Prevention and Control Center

• Chunrong Li · Yanji Brain Hospital

• Aimin Wu · Yanji Brain Hospital

• Xiangzhu Bai · Antu Tuberculosis Prevention and Control Center

• Shaorong Deng · People's Hospital Of Zhongxiang

• Shaoguang Yang · Tianjin Xiqing Hospital

• Guohong Ge · People's Hospital Of Zhenjiang

• Xuebing Yan · The Affiliated Hospital of Xuzhou Medical University

• Sheng Huang · People's Hospital Of Songzi

• Gongying Chen · The Affiliated Hospital of Hangzhou Normal University

• Ping Li · Tianjin Second People's Hospital

• Jiehua Li · The First Affiliated Hospital of Anhui Medical University

• Weiwei Kang · Beijing YouAn Hospital

Eligibility

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2016-04-30

Primary Completion

2030-12-31

Completion

2030-12-31

Countries

• China

Study Locations