Real-Life Effectiveness and Safety in Participants With Advanced/Metastatic Renal Cell Carcinoma Starting 1st Line Nivolumab and Ipilimumab Combination Therapy or Nivolumab Monotherapy After Prior Therapy
NCT02940639 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 499
Last updated 2025-07-11
Summary
The purpose of this study is to estimate overall survival over a 5-year follow-up period among adult participants with advanced/metastatic kidney cancer, starting 1st line nivolumab and ipilimumab combination therapy or nivolumab monotherapy after prior therapy, in real-life conditions in Germany
Conditions
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Bristol-Myers Squibb · Bristol-Myers Squibb
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-10-27
- Primary Completion
- 2025-06-03
- Completion
- 2025-06-03
Countries
- Germany
Study Locations
More Related Trials
-
Study of Nivolumab in Combination With Ipilimumab Compared to the Standard of Care (Extreme Regimen) as First Line Treatment in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
NCT02741570 ·Status: COMPLETED ·Phase: PHASE3
-
A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)
NCT06064097 ·Status: RECRUITING ·Phase: PHASE2
-
Study of Nivolumab in Combination With Ipilimumab Versus Nivolumab in Combination With Ipilimumab Placebo in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
NCT02823574 ·Status: COMPLETED ·Phase: PHASE2
-
Nivolumab Plus Metformin in Metastatic Renal Cell Carcinoma
NCT06884683 ·Status: TERMINATED ·Phase: PHASE2
-
Adjuvant Nivolumab After Salvage Resection in Head and Neck Cancer Patients Previously Treated With Definitive Therapy
NCT03355560 ·Status: COMPLETED ·Phase: PHASE2
-
Definitive Chemo-Radiotherapy for Regionally Advanced Head and Neck Cancer With or Without Up-front Neck Dissection
NCT02918955 ·Status: COMPLETED ·Phase: PHASE3
-
Observational Study of Nivolumab in Participants in Germany With Squamous Cell Carcinoma of the Head and Neck (SCCHN) Progressing on or After Platinum-Based Therapy
NCT03114163 ·Status: COMPLETED
-
Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma
NCT05112601 ·Status: RECRUITING ·Phase: PHASE2
-
PI3K Inhibitor BKM120 and Cetuximab in Treating Patients With Recurrent or Metastatic Head and Neck Cancer
NCT01816984 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Safety Testing of Adding Nivolumab to Chemotherapy in Patients With Intermediate and High-Risk Local-Regionally Advanced Head and Neck Cancer
NCT02764593 ·Status: COMPLETED ·Phase: PHASE1
-
Induction TPN Followed by Nivolumab With Radiation in Locoregionally Advanced Laryngeal and Hypopharyngeal Cancer
NCT03894891 ·Status: COMPLETED ·Phase: PHASE2
-
ImmunoModulation by the Combination of Ipilimumab and Nivolumab Neoadjuvant to Surgery In Advanced or Recurrent Head and Neck Carcinoma
NCT03003637 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Hypofractionated Radiotherapy and Concurrent Cisplatin for Head and Neck Cancer
NCT03194061 ·Status: UNKNOWN ·Phase: NA
-
Neoadjuvant Nivolumab for Oral Cancer Combined With FDG and Anti-PD-L1 PET/CT Imaging for Response Prediction
NCT03843515 ·Status: UNKNOWN ·Phase: PHASE1
-
Stereotactic Body Radiotherapy and Concurrent Cisplatin for Re-Irradiation of Unresectable, Recurrent Squamous Cell Carcinomas of Head and Neck
NCT02158234 ·Status: COMPLETED ·Phase: PHASE1
-
Nivolumab in Recurrent and/or Metastatic SCCHN
NCT03226756 ·Status: COMPLETED ·Phase: PHASE2
-
Neoadjuvant Targeting of Myeloid Cell Populations in Combination With Nivolumab in Head & Neck Ca
NCT04848116 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study of Nivolumab in Patients With Head and Neck Cancer.
NCT04050761 ·Status: COMPLETED
-
Nivolumab or Nivolumab Plus Cisplatin, in Combination With Radiotherapy in Patients With Cisplatin-ineligible or Eligible Locally Advanced Squamous Cell Head and Neck Cancer
NCT03349710 ·Status: COMPLETED ·Phase: PHASE3
-
Testing the Addition of an Anti-cancer Immune Therapy Drug (Nivolumab) to the Usual Chemotherapy Treatment (Cisplatin or Carboplatin With Gemcitabine) for Recurrent or Metastatic Nasopharyngeal Cancer
NCT04458909 ·Status: TERMINATED ·Phase: PHASE3
-
Predictive Biomarkers for Response to Nivolumab in Head and Neck Squamous Cell Carcinoma
NCT03652142 ·Status: UNKNOWN
-
Re-Radiochemotherapy and Pembrolizumab vs. Immuno(Chemo)Therapy for Locoregionally Recurrent PD-L1 Positive (CPS≥1) HNSCC
NCT07026474 ·Status: RECRUITING ·Phase: PHASE3
-
Neoadjuvant Iparomlimab and Tuvonralimab Plus Chemotherapy-eclipse for Locally Advanced Cervical Cancer (NICE-CC)
NCT07055399 ·Status: RECRUITING ·Phase: PHASE2
-
Radiotherapy With Cisplatin vs. Docetaxel-cetuximab in HNSCC: ERCC1 Biomarker Enrichment and Interaction Design
NCT02128906 ·Status: RECRUITING ·Phase: PHASE2
-
A Randomized Phase II Study on the Optimization of Immunotherapy in Squamous Carcinoma of the Head and Neck
NCT03620123 ·Status: COMPLETED ·Phase: PHASE2