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Effect of aPDT on Deep Caries in Permanent Tooth

NCT02929914 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2023-09-21

No results posted yet for this study

Summary

The aim of this study is to assess the clinical effect of aPDT on deep caries in permanent teeth. Half of the deep caries will receive aPDT disinfect in restorative treatment procedure, while the other half will receive sodium 0.9% saline in restorative treatment procedure.

Conditions

  • Dental Caries

Interventions

PROCEDURE

Local anesthesia and rubber dam isolation

Local anesthesia was performed. Tooth was isolated using a rubber dam isolation in order to collect the dentin samples.

PROCEDURE

Incomplete caries removal and microbiological samples collection

Partial carious tissue was removed with conventional dentinal curette and collection of dentin with a spoon (1#) was performed.

PROCEDURE

Dentin washed with sodium 0.9% saline

The remaining dentin was dipped in sodium 0.9% saline for 2min.

PROCEDURE

Antimicrobial Photodynamic Therapy

The remaining dentin was disinfected with aPDT for 2 min.

PROCEDURE

Microbiological samples collection and Indirect pulp treatment

A new dentin collection was performed after this treatment at another site of the cavity. Then teeth were conventionally restored using the following materials: calcium hydroxide lining material and resin (Z350,3M).

Sponsors & Collaborators

  • Fujian Medical University

    lead OTHER

Principal Investigators

  • Xiaojing Huang, PhD · School and Hospital of stomatology, Fujian Medical University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-06-30
Primary Completion
2024-12-31
Completion
2025-12-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02929914 on ClinicalTrials.gov