Fluorine F 18 Clofarabine PET/CT in Imaging Patients With Autoimmune or Inflammatory Diseases
NCT02925351 · Status: COMPLETED · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 8
Last updated 2020-09-04
Summary
This pilot trial studies how well fluorine F 18 clofarabine positron emission tomography (PET)/computed tomography (CT) works in imaging patients with autoimmune or inflammatory diseases. Fluorine F 18 clofarabine is an imaging agent or tracer which may be taken up by inflammatory tissue in the body. Diagnostic imaging, such as PET/CT scans, can be used to measure the amount of injected tracer that is taken up by inflammatory tissue. PET/CT scan may help to determine how fluorine F 18 clofarabine is distributed throughout the body.
Conditions
- Autoimmune Disease
- Crohn Disease
- Inflammatory Disorder
- Rheumatoid Arthritis
- Systemic Lupus Erythematosus
- Takayasu Arteritis
Interventions
- PROCEDURE
-
Computed Tomography
Undergo PET/CT scan
- RADIATION
-
Fluorine F 18 Clofarabine
Given IV
- PROCEDURE
-
Positron Emission Tomography
Undergo PET/CT scan
Sponsors & Collaborators
-
Jonsson Comprehensive Cancer Center
lead OTHER
Principal Investigators
-
Martin Allen-Auerbach · UCLA / Jonsson Comprehensive Cancer Center
Study Design
- Allocation
- NA
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-01-25
- Primary Completion
- 2018-04-30
- Completion
- 2018-04-30
- FDA Drug
- Yes
Countries
- United States
Study Locations
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