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ROCOCO - Adaptive IMRT Versus IMPT in Head and Neck Cancer

NCT02908386 · Status: WITHDRAWN · Type: OBSERVATIONAL

Last updated 2016-09-21

No results posted yet for this study

Summary

Given the lack of evidence for the benefit of particle therapy in relevant cases, he investigators proposed an in silico trial to investigate the dosimetric effect of contour changes for OAR as well as tumor during chemoradiation in H\&N patients. Photon and proton-therapy will be compared based on dosimetric data on 7 time points during treatment combined with plan robustness. In that way the investigators will be able to assess and compare the optimal timing for replanning for photon and proton therapy.

A database of the University of Pennsylvania (Upenn) consists of 10 patients with head and neck tumors treated with chemo-radiation. Contrast-enhanced CT scans were acquired prior and during RT (T1-T7)

Conditions

  • Head and Neck Neoplasms

Sponsors & Collaborators

Principal Investigators

  • Philippe Lambin, Prof dr · Maastro Clinic, The Netherlands

Eligibility

Min Age
19 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-11-30
Primary Completion
2016-06-30
Completion
2016-11-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02908386 on ClinicalTrials.gov