Memory and MRI Changes With Hippocampus Avoidance Prophylactic Cranial Irradiation(HA-PCI) for Small Cell Lung Cancer(SCLC)
NCT02906384 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 154
Last updated 2016-10-10
Summary
This is a prospective, randomized phase-II study observing the memory preservation and functional brain MRI changes with conformal avoidance of the hippocampal neural stem-cell compartment during prophylactic cranial irradiation for small cell lung cancer patients.
Conditions
Interventions
- RADIATION
-
hippocampus avoidance
conformal avoidance of the hippocampal neural stem-cell compartment during prophylactic cranial irradiation
Sponsors & Collaborators
-
Zhejiang Cancer Hospital
lead OTHER
Principal Investigators
-
Ming Chen, PHD · Zhejiang Cancer Hospital
-
Yue Kong · Zhejiang Cancer Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-10-31
- Primary Completion
- 2018-10-31
- Completion
- 2020-10-31
Countries
- China
Study Locations
More Related Trials
-
PCI for Patients With ES-SCLC After RCT:a Prospective Randomized Study
NCT04535739 ·Status: UNKNOWN ·Phase: PHASE3
-
Watchful Observation of Patients With LD-SCLC Instead of the PCI
NCT04168281 ·Status: UNKNOWN ·Phase: NA
-
Prophylactic Cranial Irradiation (PCI) Versus no PCI in Non Small Cell Lung Cancer After a Response to Chemotherapy
NCT00745797 ·Status: TERMINATED ·Phase: PHASE3
-
PET/CT Scan as a Tool to Rationalize the Treatment of of Advanced NSCLC Patients Undergoing First Chemotherapy
NCT02035683 ·Status: UNKNOWN ·Phase: NA
-
99mTc-H7ND SPECT/CT Imaging in NSCLC
NCT05999214 ·Status: RECRUITING ·Phase: NA
-
Functional Image and Molecular Markers to Predict Treatment Outcomes in Lung Cancer
NCT02117440 ·Status: TERMINATED
-
Utility of Routine Cervical Mediastinoscopy in Clinical Stage I Non-Small Cell Lung Cancer (NSCLC)
NCT01146366 ·Status: COMPLETED
-
68Ga-grazytracer PET/CT for Early Assessment of Response to Neoadjuvant Immunotherapy in Resectable NSCLC
NCT06756217 ·Status: RECRUITING
-
Thoracic Re-irradiation For Locoregionally Recurrent Non-small Cell Lung Cancer
NCT04275687 ·Status: UNKNOWN ·Phase: PHASE2
-
Stereotactic Radiosurgery for the Treatment of Patients With Small Cell Lung Cancer Brain Metastasis
NCT04516070 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Pilot Study of Regional Lung Ventilation
NCT03077113 ·Status: COMPLETED ·Phase: NA
-
Study on Prevalence and Impact of Brain Metastases on Survival in Lung Cancer by Line of Treatment
NCT06557967 ·Status: COMPLETED
-
A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain
NCT05419076 ·Status: RECRUITING ·Phase: PHASE2
-
A Prospective Study of Variation in Breath Holding Times at Various Phases of Respiration During the Course of Radiotherapy Including the Effect of Respiratory Training in Lung Cancer Patients
NCT01429766 ·Status: UNKNOWN ·Phase: PHASE2
-
Telephonic Contact and Subsequent Physical Follow up Treated Lung Cancer Patients
NCT01133067 ·Status: COMPLETED
-
Cranial Radiotherapy Plus Chemoimmunotherapy in Untreated Driver-mutation Negative NSCLC With Stable Brain Metastasis
NCT06501391 ·Status: RECRUITING ·Phase: PHASE2
-
Study of Changes of Lymphocyte Subsets in Chemotherapy Course of Patients With Non-small Cell Lung Cancer
NCT02202655 ·Status: UNKNOWN
-
Searching for Predictive Biomarkers of Efficacy in Small Cell Lung Cancer Patients Treated With Chemotherapy-immunotherapy Combination Using Imaging Mass Cytometry (HYPE)
NCT06558903 ·Status: ACTIVE_NOT_RECRUITING
-
Efficacy and Safety of Durvalumab in Non-Small Cell Lung Cancer With Leptomeningeal Metastasis
NCT04356222 ·Status: UNKNOWN ·Phase: PHASE4
-
Chemo-immunotherapy Induction Followed by Hypo-radiotherapy in LA-NSCLC(CHIC)
NCT05784142 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Cognitive Screening in Lung Cancer Patients
NCT06727370 ·Status: RECRUITING
-
Cognition and Patients With Lung Cancer
NCT07160751 ·Status: NOT_YET_RECRUITING
-
Feasibility Study of Enhanced MRI for Early Stage Non Small Cell Lung Cancer (NSCLC)
NCT01799135 ·Status: TERMINATED ·Phase: NA
-
Deep Learning Signature for Predicting Occult Nodal Metastasis of Clinical N0 Lung Cancer
NCT05425134 ·Status: UNKNOWN
-
Detection of Early Metastases in Patients With Stage I Non-small Cell Lung Cancer
NCT00003006 ·Status: COMPLETED