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Transcutaneous Oxygen as a Predictor of Wound Healing Complications in Preoperatively Radiated Soft Tissue Sarcoma

NCT02897128 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 39

Last updated 2021-07-20

No results posted yet for this study

Summary

Wound complications after sarcoma resection are frequent and potentially devastating problem. The burden of surgical wound complications in the lower extremity after preoperative external beam radiation therapy (EBRT) for soft tissue sarcoma is estimated at 43%. A noninvasive method of predicting complications would be extremely beneficial. The aim of this study is to evaluate the relationship between preoperative skin oxygenation and wound outcomes in a multi-center prospective analysis. This information could lead to a change in practice regarding surgical timing and adjunctive interventions to improve wound healing outcomes.

Conditions

  • Sarcoma, Soft Tissue

Interventions

OTHER

Observational Only - Transcutaneous Oxygen Measurement

The transcutaneous oxygen at your surgical site will be measured at three time points prior to your surgery.

Sponsors & Collaborators

  • University of Iowa

    collaborator OTHER

  • University of Florida

    collaborator OTHER

  • University of Oklahoma

    collaborator OTHER

  • Orthopedic Research and Education Foundation

    collaborator OTHER

  • Musculoskeletal Tumor Society

    collaborator UNKNOWN

  • The Cleveland Clinic

    lead OTHER

Principal Investigators

  • Lukas M Nystrom, MD · The Cleveland Clinic

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-07-31
Primary Completion
2020-09-30
Completion
2021-01-15

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02897128 on ClinicalTrials.gov