Subfoveal Choroidal Thickness After Surgery for Age-related Cataracts

Summary

To compare the effects of femtosecond laser-assisted cataract surgery (FLACS) and conventional phacoemulsification surgery (CPS) on subfoveal choroidal thickness (SFCT) in age-related cataracts.

Conditions

• Cataract

Interventions

PROCEDURE

Femtosecond laser-assisted cataract surgery

A femtosecond laser (Alcon-Lensx, Alcon-Lensx, Inc.) was used in this study. After pupil dilation and topical anesthesia, the laser was docked to the eye using a curved contact lens to applanate the cornea. With the integrated OCT imaging system, the locations of the cornea and the anterior and posterior surfaces of the crystalline lens were determined. A 5.0-mm-diameter capsulotomy was created by scanning a cylindrical pattern and followed by lens fragmentation. The laser was disconnected, and the remainder of the surgery was performed as phacoemulsification (Infiniti® Vision System; Alcon, USA). Folded intraocular lenses (IOLs) were implanted in the capsular bags.

PROCEDURE

Conventional phacoemulsification cataract surgery

Phacoemulsification was performed through a temporal 3.2-mm clear corneal incision with the same machine and followed by IOLs implantation.

DRUG

Tropicamide

After pupil dilation, 1 drop of tropicamide (0.5%) was applied every 15 minutes for 3 applications

DRUG

Proparacaine hydrochloride

topical anesthesia with proparacaine hydrochloride (0.5%) was applied.

Sponsors & Collaborators

• Ministry of Health, China

  collaborator OTHER_GOV

• Sun Yat-sen University

  lead OTHER

Principal Investigators

• Haotian Lin, M.D., Ph.D · Zhongshan Ophthalmic Center, Sun Yat-sen University

• Yizhi Liu, M.D., Ph.D · Zhongshan Ophthalmic Center, Sun Yat-sen University

• Weirong Chen, M.D. · Zhongshan Ophthalmic Center, Sun Yat-sen University

Study Design

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2014-08-31

Primary Completion

2015-06-30

Completion

2015-06-30

Countries

• China

Study Locations