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C.O.R.P.U.S.: Observational Cohort of Adult and Child Inflammatory Arthritis in France

NCT02886689 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 5400

Last updated 2016-09-01

No results posted yet for this study

Summary

C.O.R.P.U.S. is the first French observatory of care practices in active inflammatory rheumatism of children and adults: rheumatoid arthritis, spondylarthropathy, and idiopathic juvenile arthritis, established under the auspices of national health authorities.

Its goal is to document safety, effectiveness in routine practice of various therapy, including biotherapy, of prescription or non-prescription over 5 years.

A cohort will be constituted including any new case of active disease (DAS 28 \> 3,2, BASDAI \> 4, failure of methotrexate), without previous prescription of biotherapy. Therefore, it will be possible to have patients non exposed to biotherapy (non indication, refusal, contraindication) compared to patients exposed to biotherapy, and to monitor adverse events occurrence as well as effectiveness in routine practice over time, according to prescription, maintenance or switch of various therapies.

Conditions

  • Arthritis, Rheumatoid
  • Spondylitis, Ankylosing
  • Arthritis, Psoriatic
  • Arthitis, Juvenile Idiopathic

Interventions

DRUG

TNF-alpha antagonist and other biotherapy

Sponsors & Collaborators

  • Central Hospital, Nancy, France

    lead OTHER

Principal Investigators

  • Francis Guillemin, MD, PhD · Central Hospital, Nancy, France

  • Jacques Benichou, MD, PhD · CHU, Rouen, France

  • Alain Sasraux, MD, PhD · CHU de la Cavale Blanche, Brest, France

  • Loic Guillevin, MD, PhD · Hopital Cochin, Paris, France

  • Jean Sibilia, MD, PhD · CHU Hautepierre, Strasbourg, France

  • Anne Marie Prieur, MD, PhD · Hopital Necker, Paris , France

  • Daniel Wendling, MD, PhD · CHU Minioz, Besançon, France

Eligibility

Min Age
3 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-01-31
Primary Completion
2010-12-31
Completion
2011-12-31

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02886689 on ClinicalTrials.gov