Pancreatic Cancer Registry: For Any Person With a Personal or Family History

NCT02886247 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 12000

Last updated 2025-07-25

No results posted yet for this study

Summary

The NFPTR was established in 1994 to find the causes of pancreatic cancer. In brief, the investigators are interested in both the genetic and non-genetic causes of pancreatic cancer. The investigators are particularly interested in finding the genes that cause pancreatic cancer to cluster in some families. Up to 10% of pancreatic cancer patients have another close relative who has also developed pancreatic cancer. This clustering of pancreatic cancers in families has yet to be explained; however, the investigators continue to identify new familial pancreatic cancer genes that explain this clustering in subsets of families. For example, in 2009 and 2012 the investigators discovered that mutations in the PALB2 and ATM genes jointly account up to 5% of the clustering of pancreatic cancer in families.

Conditions

  • Pancreatic Cancer, ATM, BRCA, Hereditary Cancer

Sponsors & Collaborators

Principal Investigators

  • Alison Klein, PhD, MHS · Johns Hopkins University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
1994-06-30
Primary Completion
2030-06-30
Completion
2032-12-31

Countries

  • United States

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02886247 on ClinicalTrials.gov