Rifaximin Modify the Pathogenesis of Non-Alcoholic Fatty Liver Disease (NAFLD)
NCT02884037 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 50
Last updated 2017-08-11
Summary
In this multicentric, double-blind, randomized,placebo-controlled study, the investigators hypothesized that rifaximin might act on Gram-negative bacteria and intestinal bacterial overgrowth(IBO) thereby inhibiting lipopolysaccharides(LPS)-mediated proinflammatory cytokine production. This work evaluates the efficacy of 6 months administration of rifaximin in NAFLD patients.
Conditions
- Non-alcoholic Fatty Liver Disease
Interventions
- DRUG
-
Rifaximin group 1
Rifaximin: 1100mg/day, 550 mg tablets 1 × 2 before meals
Sponsors & Collaborators
-
Mansoura University
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2012-05-31
- Primary Completion
- 2015-05-31
- Completion
- 2016-10-31
Countries
- Egypt
Study Locations
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