Trial Outcomes & Findings for The Healthy Weigh Study (NCT NCT02878343)

NCT ID: NCT02878343

Last Updated: 2024-10-23

Results Overview

Change in mean weight (lbs.) from baseline to 18 months

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

344 participants

Primary outcome timeframe

Baseline to 18 months

Results posted on

2024-10-23

Participant Flow

Participant milestones

Participant milestones
Measure
Incentives
Daily lottery type incentives tied to achievement of weight loss goals Incentives: Daily lottery type incentives tied to achievement of weight loss goals
Environmental Strategies
Individually tailored environmental strategies around food intake and physical activity; automated text/emails sent from study website platform Environmental strategies: Individually tailored environmental strategies around food intake and physical activity; automated text/emails sent from study website platform
Incentive and Environmental Strategies
A combination of incentives and environmental strategies Incentives: Daily lottery type incentives tied to achievement of weight loss goals Environmental strategies: Individually tailored environmental strategies around food intake and physical activity; automated text/emails sent from study website platform
Usual Care
Standard employee wellness benefits
Overall Study
STARTED
86
86
86
86
Overall Study
COMPLETED
65
66
65
66
Overall Study
NOT COMPLETED
21
20
21
20

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

The Healthy Weigh Study

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Incentives
n=86 Participants
Daily lottery type incentives tied to achievement of weight loss goals Incentives: Daily lottery type incentives tied to achievement of weight loss goals
Environmental Strategies
n=86 Participants
Individually tailored environmental strategies around food intake and physical activity; automated text/emails sent from study website platform Environmental strategies: Individually tailored environmental strategies around food intake and physical activity; automated text/emails sent from study website platform
Incentive and Environmental Strategies
n=86 Participants
A combination of incentives and environmental strategies Incentives: Daily lottery type incentives tied to achievement of weight loss goals Environmental strategies: Individually tailored environmental strategies around food intake and physical activity; automated text/emails sent from study website platform
Usual Care
n=86 Participants
Standard employee wellness benefits
Total
n=344 Participants
Total of all reporting groups
Age, Categorical
<=18 years
0 Participants
n=99 Participants
0 Participants
n=107 Participants
0 Participants
n=206 Participants
0 Participants
n=7 Participants
0 Participants
n=31 Participants
Age, Categorical
Between 18 and 65 years
86 Participants
n=99 Participants
86 Participants
n=107 Participants
86 Participants
n=206 Participants
86 Participants
n=7 Participants
344 Participants
n=31 Participants
Age, Categorical
>=65 years
0 Participants
n=99 Participants
0 Participants
n=107 Participants
0 Participants
n=206 Participants
0 Participants
n=7 Participants
0 Participants
n=31 Participants
Age, Continuous
46.4 years
STANDARD_DEVIATION 9.5 • n=99 Participants
46.6 years
STANDARD_DEVIATION 10.9 • n=107 Participants
44.9 years
STANDARD_DEVIATION 11.1 • n=206 Participants
44.6 years
STANDARD_DEVIATION 10.6 • n=7 Participants
45.6 years
STANDARD_DEVIATION 10.5 • n=31 Participants
Sex: Female, Male
Female
61 Participants
n=99 Participants
61 Participants
n=107 Participants
61 Participants
n=206 Participants
64 Participants
n=7 Participants
247 Participants
n=31 Participants
Sex: Female, Male
Male
25 Participants
n=99 Participants
25 Participants
n=107 Participants
25 Participants
n=206 Participants
22 Participants
n=7 Participants
97 Participants
n=31 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=99 Participants
0 Participants
n=107 Participants
0 Participants
n=206 Participants
0 Participants
n=7 Participants
0 Participants
n=31 Participants
Race (NIH/OMB)
Asian
0 Participants
n=99 Participants
0 Participants
n=107 Participants
0 Participants
n=206 Participants
0 Participants
n=7 Participants
0 Participants
n=31 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=99 Participants
0 Participants
n=107 Participants
0 Participants
n=206 Participants
0 Participants
n=7 Participants
0 Participants
n=31 Participants
Race (NIH/OMB)
Black or African American
37 Participants
n=99 Participants
43 Participants
n=107 Participants
49 Participants
n=206 Participants
43 Participants
n=7 Participants
172 Participants
n=31 Participants
Race (NIH/OMB)
White
38 Participants
n=99 Participants
35 Participants
n=107 Participants
30 Participants
n=206 Participants
35 Participants
n=7 Participants
138 Participants
n=31 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=99 Participants
0 Participants
n=107 Participants
0 Participants
n=206 Participants
0 Participants
n=7 Participants
0 Participants
n=31 Participants
Race (NIH/OMB)
Unknown or Not Reported
11 Participants
n=99 Participants
8 Participants
n=107 Participants
7 Participants
n=206 Participants
8 Participants
n=7 Participants
34 Participants
n=31 Participants
Region of Enrollment
United States
86 participants
n=99 Participants
86 participants
n=107 Participants
86 participants
n=206 Participants
86 participants
n=7 Participants
344 participants
n=31 Participants

PRIMARY outcome

Timeframe: Baseline to 18 months

Change in mean weight (lbs.) from baseline to 18 months

Outcome measures

Outcome measures
Measure
Incentives
n=86 Participants
Daily lottery type incentives tied to achievement of weight loss goals Incentives: Daily lottery type incentives tied to achievement of weight loss goals
Environmental Strategies
n=86 Participants
Individually tailored environmental strategies around food intake and physical activity; automated text/emails sent from study website platform Environmental strategies: Individually tailored environmental strategies around food intake and physical activity; automated text/emails sent from study website platform
Incentive and Environmental Strategies
n=86 Participants
A combination of incentives and environmental strategies Incentives: Daily lottery type incentives tied to achievement of weight loss goals Environmental strategies: Individually tailored environmental strategies around food intake and physical activity; automated text/emails sent from study website platform
Usual Care
n=86 Participants
Standard employee wellness benefits
Mean Weight Change
-6.86 pounds
Standard Deviation 2.30
-6.86 pounds
Standard Deviation 2.08
-2.82 pounds
Standard Deviation 1.94
-0.66 pounds
Standard Deviation 1.69

Adverse Events

Incentives

Serious events: 2 serious events
Other events: 0 other events
Deaths: 0 deaths

Environmental Strategies

Serious events: 1 serious events
Other events: 0 other events
Deaths: 0 deaths

Incentive and Environmental Strategies

Serious events: 1 serious events
Other events: 0 other events
Deaths: 0 deaths

Usual Care

Serious events: 1 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Serious adverse events
Measure
Incentives
n=86 participants at risk
Daily lottery type incentives tied to achievement of weight loss goals Incentives: Daily lottery type incentives tied to achievement of weight loss goals
Environmental Strategies
n=86 participants at risk
Individually tailored environmental strategies around food intake and physical activity; automated text/emails sent from study website platform Environmental strategies: Individually tailored environmental strategies around food intake and physical activity; automated text/emails sent from study website platform
Incentive and Environmental Strategies
n=86 participants at risk
A combination of incentives and environmental strategies Incentives: Daily lottery type incentives tied to achievement of weight loss goals Environmental strategies: Individually tailored environmental strategies around food intake and physical activity; automated text/emails sent from study website platform
Usual Care
n=86 participants at risk
Standard employee wellness benefits
Cardiac disorders
Aortic valve replacement
1.2%
1/86 • Number of events 1 • Adverse event data were collected over the 18 month study period.
Definition does not differ from ct.gov definitions.
0.00%
0/86 • Adverse event data were collected over the 18 month study period.
Definition does not differ from ct.gov definitions.
0.00%
0/86 • Adverse event data were collected over the 18 month study period.
Definition does not differ from ct.gov definitions.
0.00%
0/86 • Adverse event data were collected over the 18 month study period.
Definition does not differ from ct.gov definitions.
Injury, poisoning and procedural complications
Vehicular accident
1.2%
1/86 • Number of events 1 • Adverse event data were collected over the 18 month study period.
Definition does not differ from ct.gov definitions.
0.00%
0/86 • Adverse event data were collected over the 18 month study period.
Definition does not differ from ct.gov definitions.
0.00%
0/86 • Adverse event data were collected over the 18 month study period.
Definition does not differ from ct.gov definitions.
0.00%
0/86 • Adverse event data were collected over the 18 month study period.
Definition does not differ from ct.gov definitions.
General disorders
Headaches and dizziness
0.00%
0/86 • Adverse event data were collected over the 18 month study period.
Definition does not differ from ct.gov definitions.
1.2%
1/86 • Number of events 1 • Adverse event data were collected over the 18 month study period.
Definition does not differ from ct.gov definitions.
0.00%
0/86 • Adverse event data were collected over the 18 month study period.
Definition does not differ from ct.gov definitions.
0.00%
0/86 • Adverse event data were collected over the 18 month study period.
Definition does not differ from ct.gov definitions.
Cardiac disorders
Heart attack
0.00%
0/86 • Adverse event data were collected over the 18 month study period.
Definition does not differ from ct.gov definitions.
0.00%
0/86 • Adverse event data were collected over the 18 month study period.
Definition does not differ from ct.gov definitions.
1.2%
1/86 • Number of events 1 • Adverse event data were collected over the 18 month study period.
Definition does not differ from ct.gov definitions.
0.00%
0/86 • Adverse event data were collected over the 18 month study period.
Definition does not differ from ct.gov definitions.
Vascular disorders
Brain hemorrhage
0.00%
0/86 • Adverse event data were collected over the 18 month study period.
Definition does not differ from ct.gov definitions.
0.00%
0/86 • Adverse event data were collected over the 18 month study period.
Definition does not differ from ct.gov definitions.
0.00%
0/86 • Adverse event data were collected over the 18 month study period.
Definition does not differ from ct.gov definitions.
1.2%
1/86 • Number of events 1 • Adverse event data were collected over the 18 month study period.
Definition does not differ from ct.gov definitions.

Other adverse events

Adverse event data not reported

Additional Information

Dr. Karen Glanz

UPenn

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place