Apatinib and Etoposide in Patients With Platinum Resistant or Refractory Ovarian Cancer
NCT02867956 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 35
Last updated 2026-03-10
Summary
The purpose of the study is to evaluate the efficacy and toxicity of apatinib in patients with platinum resistant or refractory ovarian cancer when combined with etoposide.
Conditions
Interventions
- DRUG
-
Apatinib
Apatinib 500mg daily, po, and it should be continued until disease progression or intolerable toxicity or patients withdrawal of consent.
- DRUG
-
Etoposide
Etoposide 50mg daily, po, day 1 to day 14, repeat every 21 days for 6 cycles
Sponsors & Collaborators
-
Sun Yat-sen University
lead OTHER
Principal Investigators
-
Xin Huang, MD · Sun Yat-sen University
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-08-10
- Primary Completion
- 2017-12-31
- Completion
- 2019-09-10
Countries
- China
Study Locations
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