National Clinical-biological Prospective Cohort of Incident Cases of Aggressive Fibromatosis (ALTITUDES)

Summary

The purpose of this study is to constitute the French largest Aggressive fibromatosis cohort.

Conditions

• Aggressive Fibromatosis

Interventions

PROCEDURE

biopsy

pre-therapeutic or post-therapeutic biopsy or resected tissues

OTHER

biobank constitution

Constitution of a biobank with pre-therapeutic or post-therapeutic biopsy or resected tissues

PROCEDURE

Coloscopy

For adult patients, a coloscopy with chromoscopy of ascending and sigmoid colon will be performed

PROCEDURE

Blood sampling (facultative)

Blood sample can be collected at diagnostic or after medically significant events (progressive disease, local or systemic treatment, pregnancy...)

OTHER

Pain evaluation

Pain evaluation (EVA scale), anxiety (HADS questionnaire), quality of life questionnaire (EORTC-QLQ-C30)

PROCEDURE

Tumor biobank realization

Realization of a tumor biobank is part of classical procedure of participating centers

Sponsors & Collaborators

• Ligue contre le cancer, France

  collaborator OTHER

• Institut Curie

  collaborator OTHER

• Hôpital de la Timone

  collaborator OTHER

• SOS Desmoid e.V.

  collaborator UNKNOWN

• APICIL funding

  collaborator UNKNOWN

• GIRCI NO

  collaborator UNKNOWN

• UNICANCER

  collaborator OTHER

• Groupement Interrégional de Recherche Clinique et d'Innovation

  collaborator OTHER

• Centre Oscar Lambret

  lead OTHER

Principal Investigators

• Nicolas PENEL, PhD · Centre Oscar Lambret

• Sébastien SALAS, PhD · Hopital Timone adultes

Study Design

Allocation

NA

Purpose

OTHER

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2016-03-22

Primary Completion

2030-11-30

Completion

2030-11-30

Countries

• France

Study Locations