The Efficacy and Safety of Endostar Combined With Taxane-based Regimens for HER-2-negative MBC Patients
NCT02865304 · Status: UNKNOWN · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 80
Last updated 2016-08-12
Summary
The purpose of the present study was to prospectively evaluate the efficacy and safety of endostar, a recombinant product of endostatin, combined with taxane-based regimens for HER-2 negative metastatic breast cancer (MBC) patients.
Conditions
- Angiogenesis
- Breast Cancer
Interventions
- DRUG
-
endostar
Sponsors & Collaborators
-
Fujian Cancer Hospital
lead OTHER_GOV
Principal Investigators
-
weiwei huang, doctor · Department of Medical Oncology, Fujian Provincial Cancer Hospital, The Teaching Hospital of Fujian Medical University, The Teaching Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou 350014, China
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-12-31
- Primary Completion
- 2017-12-31
- Completion
- 2018-12-31
More Related Trials
-
Bevacizumab and Letrozole in Treating Postmenopausal Women With Locally Advanced or Metastatic Breast Cancer That Cannot Be Removed By Surgery
NCT00305825 ·Status: COMPLETED ·Phase: PHASE2
-
Enzastaurin in Combination of Capecitabine to Treat Breast Cancer
NCT00437294 ·Status: TERMINATED ·Phase: PHASE2
-
Efficacy and Safety of TAC and Exemestane as Neoadjuvant Chemotherapy in the Postmenopausal Women With Breast Cancer
NCT01648608 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
PhIb BKM120 or BEZ235+Endocrine Treatment in Post-Menopausal Patients With Hormone Receptor + Metastatic Breast Cancer
NCT01248494 ·Status: COMPLETED ·Phase: PHASE1
-
Docetaxel Combined With Estramustine in Treating Women With Metastatic Breast Cancer
NCT00003066 ·Status: UNKNOWN ·Phase: PHASE2
-
A Trail of Neoadjuvant Endostar in Combination With Chemotherapy in Breast Cancer
NCT01907529 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
MK-2206+Endocrine Therapy in Patients With Hormone Receptor-Positive Breast Cancer
NCT01240928 ·Status: WITHDRAWN ·Phase: PHASE1
-
PTK and Letrozole in Post-menopausal Women With Advanced Breast Cancer
NCT00263198 ·Status: TERMINATED ·Phase: PHASE2
-
Neoadjuvant Chemo-endocrine Therapy Versus Chemotherapy Alone in ER-positive, HER2-negative Breast Cancer
NCT02980965 ·Status: COMPLETED ·Phase: PHASE3
-
Neoadjuvant Nab-PTX and Trastuzumab for ER Negative and HER2 Positive Breast Cancer
NCT02598310 ·Status: TERMINATED ·Phase: PHASE2
-
Neoadjuvant Study With Pyrotinib and Trastuzumab and Abraxane in Patients With HER2-enriched Breast Cancer
NCT05659056 ·Status: RECRUITING ·Phase: PHASE2
-
Real-world Effectiveness and Safety Study of T-Dxd in Chinese Metastatic Breast Cancer
NCT05594082 ·Status: UNKNOWN
-
Study Evaluating Bosutinib-Letrozole Combination Versus Letrozole Alone In Post Menopausal Women With Breast Cancer
NCT00880009 ·Status: TERMINATED ·Phase: PHASE2
-
Trial of MK-2206 + Endocrine Treatment in Patients With Hormone Receptor Positive Breast Cancer
NCT01240941 ·Status: WITHDRAWN ·Phase: PHASE2
-
Adjuvant Dual Anti-HER2 Therapy in Patients With Small, Node-negative, HER2-positive Breast Cancer
NCT04158856 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Extension Neoadjuvant Taxotere: Study of the Effects of Taxotere in Patients With Breast Cancer
NCT00206453 ·Status: TERMINATED ·Phase: PHASE2
-
Paclitaxel (Phyxol) and Cisplatin as First-line Chemotherapy for Metastatic Breast Cancer
NCT00154882 ·Status: UNKNOWN ·Phase: PHASE2
-
Trastuzumab Deruxtecan in Advanced Breast Cancer
NCT07180264 ·Status: RECRUITING
-
A Study of Weekly Taxotere and Xeloda in Metastatic Breast Cancer
NCT00214864 ·Status: COMPLETED ·Phase: PHASE2
-
Tucidinostat Combined With Metronomic Capecitabine and Endocrine Therapy for Advanced HR-positive, HER2-negative Breast Cancer After CDK4/6 Inhibitor.
NCT05411380 ·Status: UNKNOWN ·Phase: PHASE2
-
Neoadjuvant With Trastuzumab, Pyrotinib Plus Palbociclib and Fulvestrant in HER2-positive, ER-positive Breast Cancer
NCT05076695 ·Status: UNKNOWN ·Phase: PHASE2
-
Trastuzumab Plus Taxane Neoadjuvant Therapy for HER2-Positive Breast Ductal Carcinoma In Situ (DCIS) : A Phase II Study
NCT06843681 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE2
-
Tucidinostat and Nab-paclitaxel in Advanced HR+/HER2- Breast Cancer
NCT05633914 ·Status: RECRUITING ·Phase: PHASE2
-
Neoadjuvant Study of Pyrotinib in HER-2 Positive Breast Cancer
NCT04126525 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Study of Suitable Schedule of Docetaxel,Anthracycline and Cyclophosphamide in Adjuvant Therapy of Beast Cancer
NCT00525642 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3