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Australian and New Zealand Massive Transfusion Registry

NCT02863250 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 50000

Last updated 2020-09-02

No results posted yet for this study

Summary

Severe and un-stopped blood loss can occur for a number of different reasons including after a serious injury, delivery of a baby and following other medical and surgical emergencies. The investigators understanding of how to best treat people with serious bleeding is still incomplete, with many questions remaining. These include questions regarding how many people have serious bleeding events, what happens to them and the best way to treat them.

The Massive Transfusion Registry (MTR) is a register of patients who have experienced major blood loss that required a massive transfusion in any clinical setting.

The MTR uses electronic data extraction and data linkage methodologies. Pre-existing clinical data from hospital data sources, including Laboratory Information Systems (for transfusion history and laboratory results) and Health Information Services databases (for Patient demographics and admission data), are electronically extracted by staff employed at the participating hospitals. The data is then sent to the MTR Research Team, located at Monash University, where it is then linked, analysed and stored.

The establishment of a Massive Transfusion Registry will be a unique and important resource for clinicians in Australia, New Zealand and internationally, for Blood Services and for the broader community. It will provide valuable observational data regarding the types and frequency of conditions associated with critical bleeding requiring massive transfusion, the use of blood component therapy (i.e. ratios and quantities of different types of red cell to non- red cell components) and patient outcomes.

Conditions

  • Massive Transfusion
  • Trauma
  • Cardiothoracic Surgery
  • Gastrointestinal Bleeding
  • Vascular Surgery
  • Obstetric Bleeding
  • Liver Transplant

Sponsors & Collaborators

  • CSL Behring

    collaborator INDUSTRY

  • Department of Health and Human Services Victoria

    collaborator UNKNOWN

  • National Blood Authority

    collaborator OTHER

  • New Zealand Blood Service

    collaborator OTHER

  • Monash University

    lead OTHER

Principal Investigators

  • Erica Wood, MBBS · Monash University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-03-31
Primary Completion
2028-12-31
Completion
2028-12-31

Countries

  • Australia

Study Locations

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Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02863250 on ClinicalTrials.gov