Anaplastic Thyroid Cancer and Follicular Thyroid Cancer-derived Exosomal Analysis Via Treatment of Lovastatin and Vildagliptin and Pilot Prognostic Study Via Urine Exosomal Biological Markers in Thyroid Cancer Patients
NCT02862470 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 22
Last updated 2021-07-06
Summary
The investigators expected to enroll 30 patients with papillary, follicular or anaplastic thyroid cancer, and collect their urine samples before operation, immediately after operation, post-operative 3, 6 12 months. The investigators will analyze the urine exosomal proteins and probable biological markers. The investigators hope to find the prognostic biological markers via this prospective study. The investigators further hope to find newly therapeutic mechanism and medications for such patients with poorly-differentiated or anaplastic thyroid cancer.
Conditions
Sponsors & Collaborators
-
National Taiwan University Hospital
lead OTHER
Principal Investigators
-
CHIH-YUAN WANG, Doctor · Department of Internal Medicine, National Taiwan University Hospital
Eligibility
- Min Age
- 20 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-08-05
- Primary Completion
- 2018-10-31
- Completion
- 2020-08-24
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