Study of Elastographic Properties of the Clot by Technical SWIRE (Shear Wave Induced Resonance Elastography)
NCT02859532 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2019-01-07
Summary
Deep vein thrombosis (DVT) is a vascular disease characterized by the formation of a thrombus within the venous system, mainly the lower limbs. The clot structure directly influences both its location, but also its progressive profile expansion material or regression and embolic migration.
Few data are available regarding the evolution of structural properties of thrombus after an acute episode of DVT. Thrombus formation is due to the polymerization of fibrinogen into fibrin. Fibrin is a viscoelastic polymer. Its mechanical properties directly determine how the thrombus responds to forces which it is subjected.
Determining the mechanical properties of the thrombus in vivo and ex vivo is expected to study its evolutionary properties.
Conditions
- Deep Vein Thrombosis
Interventions
- RADIATION
-
elastography SWIRE
Sponsors & Collaborators
-
University Hospital, Grenoble
lead OTHER
Principal Investigators
-
Gilles PERNOD · University Hospital, Grenoble
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-01-31
- Primary Completion
- 2019-02-28
- Completion
- 2019-02-28
Countries
- France
Study Locations
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