Trial Outcomes & Findings for Intracochlear Potentials: Volta Study (NCT NCT02852330)

NCT ID: NCT02852330

Last Updated: 2025-02-10

Results Overview

Gather normative voltage tomography data for retrospective analysis. After insertion of the electrode array, TIM measurements will be taken from each subject using the cochlear implant system and Surgical Assistant Research Tool software. A Tip Foldover (TFO) in the software and x-rays will be used to identify any occurrence of a tip foldover.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

20 participants

Primary outcome timeframe

intraoperatively during and/or immediately after electrode insertion into the cochlea, with a measurement time of approximately 10 minutes.

Results posted on

2025-02-10

Participant Flow

Participant milestones

Participant milestones
Measure
Voltage Tomography
Voltage tomography measurements will be made with the SA16 research software and CS19 (1.6.2) software during and/or immediately after electrode insertion during cochlear implantation and at scheduled post-operative clinical visits. SA16 research software: Software for measurement of voltage tomography intraoperatively. CS19 (1.6.2): Software for measurement of voltage tomography post-operatively.
Overall Study
STARTED
20
Overall Study
COMPLETED
20
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Race and Ethnicity were not collected from any participant.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Voltage Tomography
n=20 Participants
Voltage tomography measurements will be made with the SA16 research software and CS19 (1.6.2) software during and/or immediately after electrode insertion during cochlear implantation and at scheduled post-operative clinical visits. SA16 research software: Software for measurement of voltage tomography intraoperatively. CS19 (1.6.2): Software for measurement of voltage tomography post-operatively.
Age, Continuous
70.3 years
n=20 Participants
Sex: Female, Male
Female
10 Participants
n=20 Participants
Sex: Female, Male
Male
10 Participants
n=20 Participants
Region of Enrollment
Australia
20 participants
n=20 Participants

PRIMARY outcome

Timeframe: intraoperatively during and/or immediately after electrode insertion into the cochlea, with a measurement time of approximately 10 minutes.

Gather normative voltage tomography data for retrospective analysis. After insertion of the electrode array, TIM measurements will be taken from each subject using the cochlear implant system and Surgical Assistant Research Tool software. A Tip Foldover (TFO) in the software and x-rays will be used to identify any occurrence of a tip foldover.

Outcome measures

Outcome measures
Measure
Voltage Tomography
n=20 Participants
Voltage tomography measurements will be made with the SA16 research software and CS19 (1.6.2) software during and/or immediately after electrode insertion during cochlear implantation and at scheduled post-operative clinical visits. SA16 research software: Software for measurement of voltage tomography intraoperatively. CS19 (1.6.2): Software for measurement of voltage tomography post-operatively.
Normative Voltage Tomography Data
Nominal TIMs
19 Participants
Normative Voltage Tomography Data
Anomalous TIMs
1 Participants
Normative Voltage Tomography Data
Correct TIP detection
19 Participants
Normative Voltage Tomography Data
Incorrect TIP detection
1 Participants

Adverse Events

Voltage Tomography

Serious events: 1 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Serious adverse events
Measure
Voltage Tomography
n=20 participants at risk
Voltage tomography measurements will be made with the SA16 research software and CS19 (1.6.2) software during and/or immediately after electrode insertion during cochlear implantation and at scheduled post-operative clinical visits. SA16 research software: Software for measurement of voltage tomography intraoperatively. CS19 (1.6.2): Software for measurement of voltage tomography post-operatively.
Cardiac disorders
Cardiac arrest
5.0%
1/20 • Number of events 1 • 12 months

Other adverse events

Adverse event data not reported

Additional Information

Bernadette Pickering

Cochlear

Phone: +61296115909

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place