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Pharmacokinetics of Post Operative Cefuroxime in Infants Undergoing Cardiac Surgery

NCT02850250 · Status: WITHDRAWN · Type: OBSERVATIONAL

Last updated 2019-01-10

No results posted yet for this study

Summary

* To evaluate plasma concentrations of Cefuroxime in this patient population
* To determine if certain pathophysiological and/or iatrogenic conditions alter the pharmacokinetics in this patient group.
* To develop a rational physiological population pharmacokinetic model that describes plasma concentrations of medications in these patients.

Conditions

  • Cardiac Event

Interventions

DRUG

Cefuroxime

Patients selected and treated as per normal pathway of care. Drugs will be prescribed as per standard Alder Hey Policy at the doses defined in the hospital policy Cefuroxime 50mg/kg 8 hourly (12 hourly if less than 7 days of age, or undergoing peritoneal dialysis - maximum 1.5grams per dose)

Sponsors & Collaborators

  • Alder Hey Children's NHS Foundation Trust

    lead OTHER

Eligibility

Max Age
3 Months
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-07-31
Primary Completion
2019-10-31
Completion
2019-10-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02850250 on ClinicalTrials.gov