Combination of Rituximab and NK Immunotherapy for B Lymphoma
NCT02843061 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2019-09-12
Summary
The aim of this study is the safety and efficacy of Rituximab plus NK immunotherapy to recurrent B lymphoma.
Conditions
- B-cell Lymphoma Recurrent
Interventions
- DRUG
- BIOLOGICAL
-
NK immunotherapy
Each time 10 billion cells, 4 times in all,i.v.
Sponsors & Collaborators
-
Shenzhen Hank Bioengineering Institute
collaborator OTHER -
Fuda Cancer Hospital, Guangzhou
lead OTHER
Principal Investigators
-
Jibing Chen, MD, PhD · Fuda Cancer Hospital, Guangzhou
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 30 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-07-01
- Primary Completion
- 2017-07-01
- Completion
- 2019-07-01
Countries
- China
Study Locations
More Related Trials
-
γδT Cells Immunotherapy in Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma (NHL)
NCT04028440 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
A Clinical Study of Hanlikang and BTK Inhibitors in the Treatment of Newly Diagnosed Mantle Cell Lymphoma
NCT05506410 ·Status: RECRUITING
-
Study of Recombinant Interleukin 21 in Combination With Rituxan for Non-Hodgkin's Lymphoma
NCT00347971 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Chemotherapy and Rituximab in Treating Young Patients With Recurrent or Refractory Non-Hodgkin's Lymphoma or Acute Lymphoblastic Leukemia
NCT00058461 ·Status: TERMINATED ·Phase: PHASE2
-
Zanubrutinib, in Combination With Lenalidomide, With or Without Rituximab in Participants With Relapsed/Refractory Diffuse Large B-Cell Lymphoma
NCT04436107 ·Status: COMPLETED ·Phase: PHASE1
-
A Trial to Compare Ibrutinib Versus Lenalidomide in Combination With MRE-chemotherapy for Adult Patients With Recurrent/Refractory Primary Central Nervous System Lymphoma (PCNSL)
NCT04129710 ·Status: RECRUITING ·Phase: PHASE2
-
Rituximab Plus Interleukin-2 in Treating Patients With Hematologic Cancer
NCT00010192 ·Status: COMPLETED ·Phase: PHASE1
-
Rituximab Plus Fludarabine in Treating Patients With Waldenstrom's Macroglobulinemia
NCT00020800 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Relapsed/ Refractory B-cell Non- Hodgkin Lymphoma
NCT07125872 ·Status: RECRUITING ·Phase: PHASE2
-
BTK Inhibitor BGB-3111 in Chinese Participants With Diffuse Large B-Cell Lymphoma (Non-GCB) and Indolent Lymphoma (FL and MZL)
NCT03520920 ·Status: COMPLETED ·Phase: PHASE2
-
Ibrutinib Combined With Rituximab for Treatment of Relapsed Refractory MYD88 and CD79A/B (or CD79B Alone) DLBCL Who Have Received at Least Two Prior Therapies
NCT04994626 ·Status: UNKNOWN ·Phase: PHASE2
-
Rituximab and Yttrium Y 90 Ibritumomab Tiuxetan in Treating Patients With Recurrent Primary CNS Lymphoma
NCT00082836 ·Status: COMPLETED ·Phase: NA
-
An Investigational Immuno-therapy Study to Determine the Safety of Urelumab Given in Combination With Nivolumab in Solid Tumors and B-cell Non-Hodgkin's Lymphoma
NCT02253992 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
R Retreatment in 1st Relapsed DLBCL
NCT00980304 ·Status: UNKNOWN ·Phase: PHASE2
-
Study of Ibrutinib in Combination With Rituximab in Previously Untreated Subjects With Follicular Lymphoma
NCT01980654 ·Status: COMPLETED ·Phase: PHASE2
-
Rituximab Combined With Chidamide and Lenalidomide for r/r AITL
NCT04319601 ·Status: UNKNOWN ·Phase: NA
-
CD30 CAR T Cells, Relapsed CD30 Expressing Lymphoma (RELY-30)
NCT02917083 ·Status: RECRUITING ·Phase: PHASE1
-
Study of BKM120 & Rituximab in Patients With Relapsed or Refractory Indolent B-Cell Lymphoma
NCT02049541 ·Status: COMPLETED ·Phase: PHASE1
-
Immunobridging/Maintenance Therapy Versus Non-bridging Therapy in CAR-T Therapy for Low-risk R/R B-NHL
NCT06695013 ·Status: RECRUITING ·Phase: PHASE2
-
Rituximab and Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With B-Cell Non-Hodgkin's Lymphoma
NCT00278408 ·Status: COMPLETED ·Phase: PHASE3
-
A Phase II Clinical Trial of Suppression of Human Antimouse Antibody and Human Antitoxin Response to Immunotoxin LMB-1 by Rituximab
NCT00001805 ·Status: COMPLETED ·Phase: PHASE2
-
Rituximab and Interleukin-12 in Treating Patients With B-Cell Non-Hodgkin's Lymphoma
NCT00026182 ·Status: COMPLETED ·Phase: PHASE2
-
Glofitamab in Chinese Patients With R/R DLBCL
NCT06481826 ·Status: RECRUITING
-
A Study to Evaluate the Safety, Tolerability, and Efficacy of Relatlimab in Relapsed or Refractory B-Cell Malignancies
NCT02061761 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
An Efficacy and Tolerability Study of Bortezomib in Combination With Rituximab Standard Therapy in Participants With Relapsed or Refractory Follicular Lymphoma
NCT01902862 ·Status: TERMINATED ·Phase: PHASE2