Microbial Epidemiology and Chlorhexidine Suscebtibily of Oropharyngeal and Intestinal Colonization
NCT02840656 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 100
Last updated 2023-06-12
Summary
In this prospective observational study we aim to determine the prevalence of oropharyngeal and rectal Gram-negative bacilli colonization in healthy subjects, and their susceptibility to chlorehexidine. We plan to recruit 100 healthy volunteers secondary endpoints are to determine the phylogentic characteristics of E. coli isolates; to compare the phylogentic characteristics of oropharyngeal and rectal of predominant GNB colonization.
Conditions
- Oropharyngeal Gram-negative Bacilli Colonization
Interventions
- OTHER
-
oropharyngeal swabbing
microbiological sampling will be performed on buccal mucosa with standard swab. only one sample will be done
- OTHER
-
rectal swabbing
same process as oropharyngeal swabbing will be used to collect rectal microbiological sample
Sponsors & Collaborators
-
Assistance Publique - Hôpitaux de Paris
lead OTHER
Principal Investigators
-
Jonathan MESSIKA, MD · Hopital Louis Mourier - Assistance Publique Hopitaux de Paris
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2016-09-30
- Primary Completion
- 2017-08-16
- Completion
- 2020-11-30
Countries
- France
Study Locations
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