A Study of Continued Treatment Among Participants Who Have Responded to Peginterferon Alfa-2a (Pegasys®) or Recombinant Interferon Alfa-2a (Roferon-A®) in Prior Clinical Studies
NCT02829775 · Status: COMPLETED · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 9
Last updated 2017-01-09
Summary
This open label extension study will give an opportunity to the participants that have responded to the treatment with Pegylated-Interferon Alfa-2a (Pegasys) or Recombinant Interferon Alfa-2a (Roferon-A®) in prior clinical studies NO15753 (NCT00003542) for Renal Cell Carcinoma (RCC), NO15764 (NCT number not available) and NO16006 (NCT02736721) for Chronic Myelogenous Leukemia (CML), and NO16007 (NCT number not available) for Malignant Melanoma (MM).
Conditions
- Chronic Myelogenous Leukemia
- Malignant Melanoma
- Renal Cell Carcinoma
Interventions
- DRUG
-
Pegylated Interferon Alfa-2a
Participants will maintain the same dose they were receiving in the parent protocol.
- DRUG
-
Recombinant Interferon Alfa 2a
Participants will maintain the same dose they were receiving in the parent protocol.
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Clinical Trials · Hoffmann-La Roche
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2004-01-31
- Primary Completion
- 2008-01-31
- Completion
- 2008-01-31
Countries
- Bulgaria
- Canada
- India
- Russia
- Slovakia
- South Africa
- Spain
Study Locations
More Related Trials
-
A Phase II Study of an Anti-Tumor Immunotherapy Regimen Comprised of Pegylated Interferon-Alpha 2b and HyperAcute Melanoma Vaccine for Subjects With Advanced Melanoma
NCT00746746 ·Status: UNKNOWN ·Phase: PHASE2
-
Safety and Tolerability of Pembrolizumab (MK-3475) + Pegylated Interferon Alfa-2b and Pembrolizumab+ Ipilimumab in Participants With Advanced Melanoma or Renal Cell Carcinoma (MK-3475-029/KEYNOTE-29)
NCT02089685 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Interleukin-2 Plus Interferon Alfa in Treating Adults With Metastatic Cancer
NCT00002504 ·Status: COMPLETED ·Phase: PHASE2
-
Peptide Vaccination for Patients at High Risk for Recurrent Melanoma
NCT00059475 ·Status: COMPLETED ·Phase: PHASE2
-
Biological Therapy in Treating Patients With Metastatic Cancer
NCT00002733 ·Status: COMPLETED ·Phase: PHASE2
-
Interleukin-2 and Interferon in Treating Patients With Metastatic Kidney Cancer
NCT00416871 ·Status: COMPLETED ·Phase: PHASE3
-
Study of Interleukin-2, Interferon-alpha and Bevacizumab in Metastatic Kidney Cancer
NCT01274273 ·Status: UNKNOWN ·Phase: PHASE2
-
Interferon Alfa and Interleukin-6 in Treating Patients With Recurrent Multiple Myeloma
NCT00470093 ·Status: TERMINATED ·Phase: EARLY_PHASE1
-
Immunization With the MAGE-3.A1 Peptide Mixed With the Adjuvant CpG 7909 in Patients With Metastatic Melanoma
NCT00145145 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Vaccine Therapy Compared With Interferon Alfa in Treating Patients With Stage III Melanoma
NCT00003715 ·Status: TERMINATED ·Phase: PHASE2
-
A Dose Escalation, Dose Expansion Study to Evaluate the Safety, Tolerability, and Antitumor Activity of MEDI-575, in Subjects With Advanced Tumors.
NCT00816400 ·Status: COMPLETED ·Phase: PHASE1
-
S0916, MLN1202 in Treating Patients With Bone Metastases
NCT01015560 ·Status: COMPLETED ·Phase: PHASE2
-
An Extension Study in Participants Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study (IMbrella C)
NCT05112965 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
A Study of R1507 in Participants With Recurrent or Refractory Sarcoma
NCT00642941 ·Status: TERMINATED ·Phase: PHASE2
-
Study of a Multi-Antigen Therapeutic Vaccine in Patients With Metastatic Melanoma
NCT00613509 ·Status: TERMINATED ·Phase: PHASE2
-
Interleukin-12 Followed by Interferon Alfa in Treating Patients With Advanced Cancer
NCT00003451 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Intravenous (IV) Cergutuzumab Amunaleukin and Atezolizumab in Combination in Participants With Locally Advanced and/or Metastatic Solid Tumors
NCT02350673 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of MNRP1685A in Patients With Locally Advanced or Metastatic Solid Tumors
NCT00747734 ·Status: COMPLETED ·Phase: PHASE1
-
PF-3512676 (CPG 7909) Injection For Patients Who Completed An Oncology Study Using PF-3512676 (CPG 7909)
NCT00043368 ·Status: COMPLETED ·Phase: PHASE2
-
Testing the Combination of Two Experimental Drugs MK-3475 (Pembrolizumab) and Interferon-gamma for the Treatment of Mycosis Fungoides and Sézary Syndrome and Advanced Synovial Sarcoma
NCT03063632 ·Status: COMPLETED ·Phase: PHASE2
-
Safety Study of a Helper Peptide Vaccine Plus Adjuvant Combinations for the Treatment of Melanoma
NCT02425306 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Immunization With 8 Peptides Mixed With CpG 7909 or Montanide ISA51 in Patients With Metastatic Cutaneous Melanoma
NCT00145158 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Cyclophosphamide and Fludarabine Followed by Vaccine Therapy, Gene-Modified White Blood Cell Infusions, and Aldesleukin in Treating Patients With Metastatic Melanoma
NCT00091104 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Insulin-like Growth Factor (IGF)-Methotrexate Conjugate in the Treatment of Advanced Tumors Expressing IGF-1R
NCT02045368 ·Status: COMPLETED ·Phase: PHASE1
-
NovoTTF-200A + Pembrolizumab In Melanoma Brain Metastasis
NCT04129515 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2