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Morphological Changes of the Brain by MRI in Chronic Kidney Disease

NCT02827253 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2017-08-10

No results posted yet for this study

Summary

The purpose of this study is to describe brain´s morphological changes induced by chronic kidney disease (CKD) in advanced stages (stages 4 and 5 defined by KDOQI guidelines) and also by haemodialysis using MRI.

Based on the hypothesis that hypotension may cause damage in some organs including brain the investigators study if intradialytic hypotension (IDH) causes any type of changes in gray and white matter of the brain.

Conditions

  • Chronic Kidney Disease Requiring Chronic Dialysis

Interventions

DEVICE

MRI

MRI will be performed during interdialysis period in the haemodialysis group. MRI will be performed at the beginning of the study in predialysis group.

Sponsors & Collaborators

  • Hospital General Universitario Gregorio Marañon

    lead OTHER

Principal Investigators

  • Juan M. López Gómez, PhD · Hospital General Universitario Gregorio Marañon

  • Santiago Cedeño Mora, MD · Hospital General Universitario Gregorio Marañon

  • Manuel Desco, PhD · Hospital General Universitario Gregorio Marañon

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-06-30
Primary Completion
2018-06-30
Completion
2019-06-30

Countries

  • Spain

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02827253 on ClinicalTrials.gov