Trial Outcomes & Findings for Educational Videos to Address Racial Disparities in Implantable Cardioverter Defibrillator Therapy (NCT NCT02819973)

NCT ID: NCT02819973

Last Updated: 2021-04-21

Results Overview

Proportion of patients who have decided by 7 days to receive an ICD among patients randomized to the video intervention compared with health care provider counseling (usual care)

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

343 participants

Primary outcome timeframe

7 days

Results posted on

2021-04-21

Participant Flow

Participant milestones

Participant milestones
Measure
Racially Concordant Video
Participants watching a video in which actors are primarily of the same race (Black/African American) as the participant
Racially Discordant Video
Participants watching a video in which actors are primarily not of the same race (not Black/African American) as the participant.
Usual Care (No Video)
Standard Care/ No video
Overall Study
STARTED
114
114
115
Overall Study
COMPLETED
108
111
111
Overall Study
NOT COMPLETED
6
3
4

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Educational Videos to Address Racial Disparities in Implantable Cardioverter Defibrillator Therapy

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Racially Concordant Video
n=108 Participants
Participants watching a video in which actors are primarily of the same race (Black/African American) as the participant.
Racially Discordant Video
n=111 Participants
Participants watching a video in which actors are primarily not of the same race (not Black/African American) as the participant
Usual Care (no Video)
n=111 Participants
Standard Care/ No video
Total
n=330 Participants
Total of all reporting groups
Age, Continuous
59.0 years
n=99 Participants
59.0 years
n=107 Participants
60.1 years
n=206 Participants
59.3 years
n=7 Participants
Sex/Gender, Customized
Gender · Male
63 Participants
n=99 Participants
69 Participants
n=107 Participants
76 Participants
n=206 Participants
208 Participants
n=7 Participants
Sex/Gender, Customized
Gender · Female
44 Participants
n=99 Participants
42 Participants
n=107 Participants
35 Participants
n=206 Participants
121 Participants
n=7 Participants
Sex/Gender, Customized
Gender · Unknown
1 Participants
n=99 Participants
0 Participants
n=107 Participants
0 Participants
n=206 Participants
1 Participants
n=7 Participants
Race/Ethnicity, Customized
Black/African American
108 Participants
n=99 Participants
111 Participants
n=107 Participants
111 Participants
n=206 Participants
330 Participants
n=7 Participants
Region of Enrollment
United States
108 participants
n=99 Participants
111 participants
n=107 Participants
111 participants
n=206 Participants
330 participants
n=7 Participants

PRIMARY outcome

Timeframe: 7 days

Population: Among patients randomized to the video intervention compared with health care provider counseling (usual care) and having outcome data recorded. Video arms were combined into a single group to measure the impact of video vs. no video.

Proportion of patients who have decided by 7 days to receive an ICD among patients randomized to the video intervention compared with health care provider counseling (usual care)

Outcome measures

Outcome measures
Measure
Video
n=210 Participants
Participants randomized to watch a video about ICDs
Usual Care (no Video)
n=101 Participants
Participants randomized to usual care with no video
Proportion of Patients Saying "Yes" to ICD
Yes, want an ICD
123 Participants
60 Participants
Proportion of Patients Saying "Yes" to ICD
No or unsure about an ICD
87 Participants
41 Participants

SECONDARY outcome

Timeframe: 7 days

Population: All participants randomized to video arm for whom outcome data is available. Usual care arm is excluded from this outcome to measure the impact of racial concordance among those viewing a video.

Proportion of patients who watched a racially concordant video and who decided by 7 days to receive an ICD

Outcome measures

Outcome measures
Measure
Video
n=102 Participants
Participants randomized to watch a video about ICDs
Usual Care (no Video)
n=108 Participants
Participants randomized to usual care with no video
Proportion of Individuals Saying Yes to ICD Implant in the Racially Concordant Video
Yes, want an ICD
54 Participants
69 Participants
Proportion of Individuals Saying Yes to ICD Implant in the Racially Concordant Video
No or unsure about an ICD
48 Participants
39 Participants

SECONDARY outcome

Timeframe: Baseline preintervention and Baseline (approximately 20mins later) post intervention

Population: Among patients randomized to the video intervention compared with health care provider counseling (usual care) and having outcome data recorded. Video arms were combined into a single group to measure the impact of video vs. no video.

Difference in Knowledge Questionnaire scores before and after receiving the intervention. Range of 0 to 13, with higher score indicating greater knowledge about ICDs.

Outcome measures

Outcome measures
Measure
Video
n=218 Participants
Participants randomized to watch a video about ICDs
Usual Care (no Video)
n=111 Participants
Participants randomized to usual care with no video
Changes in Patient Knowledge (Pre and Post Intervention)
Pre-intervention knowledge score
6.0 score on a scale
Standard Deviation 2.6
6.1 score on a scale
Standard Deviation 2.8
Changes in Patient Knowledge (Pre and Post Intervention)
Post-intervention knowledge score
9.0 score on a scale
Standard Deviation 1.9
8.4 score on a scale
Standard Deviation 2.4

SECONDARY outcome

Timeframe: Baseline pre intervention and 1 week post intervention

Population: Among patients randomized to the video intervention compared with health care provider counseling (usual care) and having outcome data recorded at the specified time point. Video arms were combined into a single group to measure the impact of video vs. no video.

Difference in Decisional Conflict Scale score from baseline pre-intervention to 1 week post-intervention, range of 0-100 with higher value indicating greater conflict about the decision to receive an ICD.

Outcome measures

Outcome measures
Measure
Video
n=218 Participants
Participants randomized to watch a video about ICDs
Usual Care (no Video)
n=111 Participants
Participants randomized to usual care with no video
Changes in Decisional Conflict (Pre and Post)
Score baseline pre-intervention
34.4 score on a scale
Interval 25.0 to 44.9
37.5 score on a scale
Interval 25.0 to 46.9
Changes in Decisional Conflict (Pre and Post)
Score 1 week post-intervention
25.0 score on a scale
Interval 12.5 to 28.1
25.0 score on a scale
Interval 17.2 to 31.2

SECONDARY outcome

Timeframe: 3 Months

Population: Among patients randomized to the video intervention compared with health care provider counseling (usual care) and having outcome data recorded at the specified timepoint. Video arms were combined into a single group to measure the impact of video vs. no video.

Number of participants receiving ICD implant within 90 days of enrollment as assessed by medical record review.

Outcome measures

Outcome measures
Measure
Video
n=219 Participants
Participants randomized to watch a video about ICDs
Usual Care (no Video)
n=110 Participants
Participants randomized to usual care with no video
ICD Receipt Within 90 Days of Enrollment.
142 Participants
74 Participants

SECONDARY outcome

Timeframe: Baseline

Population: Among patients randomized to the video intervention compared with health care provider counseling (usual care) and having outcome data recorded. Video arms were combined into a single group to measure the impact of video vs. no video.

Number of minutes spent with patients during baseline visit as measured by baseline questionnaire timer

Outcome measures

Outcome measures
Measure
Video
n=201 Participants
Participants randomized to watch a video about ICDs
Usual Care (no Video)
n=110 Participants
Participants randomized to usual care with no video
Time Spent With Patients by Providers in Each Arm of the Study
18.0 minutes
Interval 9.0 to 31.0
20.0 minutes
Interval 12.0 to 39.0

SECONDARY outcome

Timeframe: 1 week

Population: Among patients randomized to the video intervention compared with health care provider counseling (usual care) and having outcome data recorded at the specified timepoint. Video arms were combined into a single group to measure the impact of video vs. no video.

Assessment of knowledge retention at one week through re-administration of baseline Knowledge Questionnaire. Scale of 0-13, with higher score indicating more knowledge about ICDs.

Outcome measures

Outcome measures
Measure
Video
n=211 Participants
Participants randomized to watch a video about ICDs
Usual Care (no Video)
n=102 Participants
Participants randomized to usual care with no video
Patient Knowledge
9.0 score on a scale
Interval 7.0 to 10.0
8.0 score on a scale
Interval 6.0 to 10.0

OTHER_PRE_SPECIFIED outcome

Timeframe: 3 Month

In-depth phone interview

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: 3 Month

In-depth phone interview

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: 1 week

In-depth phone interview

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: 3 Month

In-depth phone interview

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: 1 week

In-depth phone interview

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: 3 Month

In-depth phone interview

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: 1 week

In-depth phone interview

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: 1 week

In-depth phone interview

Outcome measures

Outcome data not reported

Adverse Events

Educational Video 1

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Educational Video 2

Serious events: 0 serious events
Other events: 0 other events
Deaths: 4 deaths

Usual Care (no Video) 3

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Kevin Thomas, MD

Duke Clinical Research Institute

Phone: 919-668-8700

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place