Chidamide With EGFR-TKI for Advanced EGFR-TKI-resistant Non-Small Cell Lung Cancer
NCT02815007 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2016-06-28
Summary
The purpose of this study is to evaluate the efficacy and safety of Chidamide with EGFR-TKI for Advanced EGFR-TKI-resistant Non-Small Cell Lung Cancer
Conditions
- Advanced EGFR-TKI-resistant Non-Small Cell Lung Cancer
Interventions
- DRUG
-
Chidamide with EGFR-TKI
Chidamide and EGFR-TKI, dosage described in arm description.
Sponsors & Collaborators
-
Yuankai Shi
lead OTHER
Principal Investigators
-
Yuankai Shi, Doctor · Cancer institute and hospital, Chinese academy of medical sciencees
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-06-30
- Primary Completion
- 2018-03-31
- Completion
- 2018-06-30
More Related Trials
-
SH-1028 Tablets Versus Placebo as Adjuvant Therapy in Resected Stage II-IIIB NSCLC With Sensitizing EGFR Mutations
NCT06080776 ·Status: RECRUITING ·Phase: PHASE3
-
Combination of Chemotherapy and Gefitinib as First-line Treatment
NCT02148380 ·Status: COMPLETED ·Phase: NA
-
A Study of Hypofractionated Radiotherapy for Limited Metastatic NSCLC Harboring Sensitizing EGFR Mutations After First Line TKI Therapy
NCT02788058 ·Status: UNKNOWN ·Phase: PHASE2
-
Study of EGFR TKI in Patients With Advanced NSCLC Harbouring EGFR Mutations
NCT06062823 ·Status: RECRUITING ·Phase: PHASE2
-
Icotinib in Non-small Cell Lung Cancer Patients With Uncommon EGFR Mutation
NCT02961270 ·Status: UNKNOWN ·Phase: PHASE2
-
LDK378 in Adult Chinese Patients With ALK-rearranged (ALK-positive) Advanced Non-small Cell Lung Cancer (NSCLC) Previously Treated With Crizotinib
NCT02040870 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Phase I/II Study of PLB1004 Combined With Platinum-based Doublet Chemotherapy in Patients With EGFR Mutation-positive
NCT07063329 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
Safety and Effectiveness Study of Chemotherapy in Combination With Erlotinib,or Sequential Erlotinib for Treatment in Patients With NSCLC
NCT02037997 ·Status: UNKNOWN ·Phase: PHASE2
-
Safety, Tolerability and Pharmacokinetics of SH-1028 in Patients With Advanced NSCLC
NCT03603262 ·Status: UNKNOWN ·Phase: PHASE1
-
A Study to Evaluate the Safety and Efficacy of SH-1028 in Locally Advanced or Metastatic NSCLC
NCT03823807 ·Status: UNKNOWN ·Phase: PHASE2
-
Third-generation EGFR-TKI Plus Anlotinib as Maintenance for NSCLC With Small Cell Transformation After EGFR-TKI Resistance
NCT06634667 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Weekly Use First-generation EGFR-TKI in the Treatment of EGFR-TKI Acquired Resistance Non-small Cell Lung Cancer (NSCLC)
NCT02575560 ·Status: COMPLETED
-
Anti-GPC3 CAR T for Recurrent or Refractory Lung Squamous Cell Carcinoma
NCT02876978 ·Status: UNKNOWN ·Phase: PHASE1
-
Phase II Trial to Evaluate the Efficacy and Safety of HM61713 as the 1st-line NSCLC Anticancer Therapy
NCT02444819 ·Status: COMPLETED ·Phase: PHASE2
-
High-dose Icotinib Treatment Beyond Progression in EGFR Mutant NSCLC
NCT02960607 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study of Zipalertinib in Patients With Advanced Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions or Other Uncommon Mutation.
NCT05967689 ·Status: RECRUITING ·Phase: PHASE2
-
Neoadjuvant HS-10296 (Almonertinib) Therapy for Potential Resectable Stage III EGFR Mutation-Positive Non-small Cell Lung Cancer
NCT04685070 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Efficacy of Targeted Therapy Combined Chemotherapy in Advanced EGFR Positive NSCLC Patients
NCT04552613 ·Status: COMPLETED ·Phase: NA
-
EGFR-TKI Combined With Concurrent or Sequential Chemotherapy for Patients of Gradual Progression
NCT03544814 ·Status: COMPLETED ·Phase: PHASE2
-
Neoadjuvant Afatinib Therapy for Potentially Resectable Stage III EGFR Mutation-Positive Lung Adenocarcinoma
NCT04201756 ·Status: COMPLETED ·Phase: PHASE2
-
Afatinib Combined With Chemotherapy as Conversion Therapy in Unresectable EGFR Sensitive Mutation-positive Stage III NSCLC
NCT06709859 ·Status: RECRUITING ·Phase: PHASE2
-
Efficacy and Safety of SCT200 in Patients With Advanced Squamous Non-small Cell Lung Cancer
NCT03808701 ·Status: UNKNOWN ·Phase: PHASE1
-
Pemetrexed vs Pemetrexed Plus Cisplatin in EGFR-mutant NSCLC Patients After First Line EGFR-TKIs Failure
NCT02725918 ·Status: UNKNOWN ·Phase: PHASE2
-
Anti-angiogenesis Combine With EGFR-TKI in Advanced Non-squamous Non Small Cell Lung Cancer
NCT03461185 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study of ZN-e4 in Subjects With Epidermal Growth Factor Receptor Mutated Non-Small Cell Lung Cancer
NCT03446417 ·Status: COMPLETED ·Phase: PHASE1