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Ascitic Fluid Microbiome in Liver Cirrhosis

NCT02813590 · Status: WITHDRAWN · Type: OBSERVATIONAL

Last updated 2024-03-15

No results posted yet for this study

Summary

Ascitic fluid microbiome is going to be investigated in this study by using internal transcripted spacer (ITS) and 16S ribosomal RNA (rRNA) polymerase chain reaction (PCR) and sequencing as conventional culture methods are lacking sensitivity regarding diagnosis of spontaneous bacterial peritonitis (SBP).

All patients with routinely performed ascitic fluid puncture and underlying liver cirrhosis are included in this study. Next generation sequencing (NGS) in ascitic fluid, skin swaps from puncture side and stool samples as well as conventional culture methods are performed to investigate the difference in the microbiome between patients with and without SBP.

Conditions

  • Ascitic Fluid, Microbiota
  • Microbiota
  • Sequence Analysis
  • Polymerase Chain Reaction

Interventions

OTHER

Ascitic fluid puncture

OTHER

Skin swaps from puncture side

OTHER

Stool samples

Sponsors & Collaborators

  • CBmed - Center for biomarker research in medicine

    collaborator UNKNOWN

  • Medical University of Graz

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-06-30
Primary Completion
2017-09-30
Completion
2017-09-30

Countries

  • Austria

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02813590 on ClinicalTrials.gov