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Sorting and Expression Profiling of Airway Cells From Humans (The SEARCH Study)

NCT02791542 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 32

Last updated 2024-02-05

No results posted yet for this study

Summary

This will be a single site, mechanistic study of asthmatic subjects and healthy, non-asthmatic controls involving a baseline characterization visit and a research bronchoscopy visit. We will identify differences in airway epithelial epigenetic enhancer signatures in asthma, by analyzing freshly isolated airway epithelial cells from healthy controls and from well-characterized subjects with asthma.

Conditions

Sponsors & Collaborators

  • National Heart, Lung, and Blood Institute (NHLBI)

    collaborator NIH

  • National Institute of Allergy and Infectious Diseases (NIAID)

    collaborator NIH

  • University of California, San Francisco

    lead OTHER

Principal Investigators

  • Nirav Bhakta, MD, PhD · University of California, San Francisco

  • Prescott Woodruff, MD, MPH · University of California, San Francisco

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-01-31
Primary Completion
2023-03-31
Completion
2023-03-31

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02791542 on ClinicalTrials.gov