Diagnosis of Pulmonary Hypertension Using Cardiac Magnetic Resonance Images
NCT02790918 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 60
Last updated 2020-08-04
Summary
In this study, study team aim to i) evaluate the accuracy of 3D IVS curvedness for prediction of RV systolic pressure (RVSP), mean pulmonary artery pressure (mPAP) and pulmonary vascular resistance (PVR) with RHC; ii) evaluate the usefulness of 3D IVS curvedness for predicting the response to vasodilator challenge with RHC, in patients clinically suspected or known to have primary PH.
Conditions
- Pulmonary Hypertension
Interventions
- OTHER
-
6MWT
Each patient will also receive 6MWT at cardiovascular rehabilitation and preventive cardiology laboratory. Besides the distance covered in meters or converted measure (such as feet) over 6 minutes, a portable metabolic system is used to measure oxygen uptake during exercise (VO2 testing) for each patient.
- OTHER
-
Cardiovascular Magnetic Resonance Imaging (CMRI)
MRI uses interaction of the magnetic properties of body tissues with strong magnetic fields to create images; for about 1 hour. Several sets of images are needed. No injection of drug or dye will be used for this procedure.
Sponsors & Collaborators
-
National Heart Centre Singapore
lead OTHER
Principal Investigators
-
Liang Zhong, PhD · National Heart Centre Singapore
Eligibility
- Min Age
- 16 Years
- Max Age
- 99 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2013-05-31
- Primary Completion
- 2019-10-31
- Completion
- 2019-10-31
Countries
- Singapore
Study Locations
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