Trial Outcomes & Findings for Validation of the Hospital Asthma Severity Score (HASS) (NCT NCT02782065)

NCT ID: NCT02782065

Last Updated: 2021-03-23

Results Overview

The inter-rater reliability (the percent of agreement among raters) for the HASS as scored by 2 individual health care providers. Inter-rater agreement refers to the agreement between the single clinician who was Rater 1 and the second clinician rating the patient (Rater 2), regardless of which clinician served as Rater 2

Recruitment status

COMPLETED

Target enrollment

58 participants

Primary outcome timeframe

4 years and 9 months

Results posted on

2021-03-23

Participant Flow

Participant milestones

Participant milestones
Measure
Pediatric Patients With Asthma
34 patients aged 7 to 18 years, and 24 patients aged 2 to 6 years Not an interventional study
Overall Study
STARTED
58
Overall Study
COMPLETED
58
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

There were two participants classified as two different races, and one participant had missing data for that question. With those extra 2 added and 1 not included, it would bring the total number in the race table to be 59.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Pediatric Patients With Asthma
n=58 Participants
34 patients aged 7 to 18 years, and 24 patients aged 2 to 6 years Not an interventional study
Age, Categorical
<=18 years
58 Participants
n=58 Participants
Age, Categorical
Between 18 and 65 years
0 Participants
n=58 Participants
Age, Categorical
>=65 years
0 Participants
n=58 Participants
Sex: Female, Male
Female
30 Participants
n=58 Participants
Sex: Female, Male
Male
28 Participants
n=58 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
13 Participants
n=58 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
36 Participants
n=58 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
9 Participants
n=58 Participants
Race/Ethnicity, Customized
Caucasian
17 participants
n=57 Participants • There were two participants classified as two different races, and one participant had missing data for that question. With those extra 2 added and 1 not included, it would bring the total number in the race table to be 59.
Race/Ethnicity, Customized
Black/African American
24 participants
n=57 Participants • There were two participants classified as two different races, and one participant had missing data for that question. With those extra 2 added and 1 not included, it would bring the total number in the race table to be 59.
Race/Ethnicity, Customized
Asian
2 participants
n=57 Participants • There were two participants classified as two different races, and one participant had missing data for that question. With those extra 2 added and 1 not included, it would bring the total number in the race table to be 59.
Race/Ethnicity, Customized
Dominican
3 participants
n=57 Participants • There were two participants classified as two different races, and one participant had missing data for that question. With those extra 2 added and 1 not included, it would bring the total number in the race table to be 59.
Race/Ethnicity, Customized
Other
4 participants
n=57 Participants • There were two participants classified as two different races, and one participant had missing data for that question. With those extra 2 added and 1 not included, it would bring the total number in the race table to be 59.
Race/Ethnicity, Customized
Unknown
9 participants
n=57 Participants • There were two participants classified as two different races, and one participant had missing data for that question. With those extra 2 added and 1 not included, it would bring the total number in the race table to be 59.
Region of Enrollment
United States
58 Participants
n=58 Participants

PRIMARY outcome

Timeframe: 4 years and 9 months

The inter-rater reliability (the percent of agreement among raters) for the HASS as scored by 2 individual health care providers. Inter-rater agreement refers to the agreement between the single clinician who was Rater 1 and the second clinician rating the patient (Rater 2), regardless of which clinician served as Rater 2

Outcome measures

Outcome measures
Measure
Pediatric Patients With Asthma
n=58 Participants
34 patients aged 7 to 18 years, and 24 patients aged 2 to 6 years Not an interventional study
Inter-rater Reliability for the Hospital Asthma Severity Score (HASS)
29 percentage of agreement between raters

PRIMARY outcome

Timeframe: 4 years and 9 months

The inter-rater reliability for the PRAM as scored by 2 individual health care providers. Inter-rater agreement refers to the agreement between the single clinician who was Rater 1 and the second clinician rating the patient (Rater 2), regardless of which clinician served as Rater 2.

Outcome measures

Outcome measures
Measure
Pediatric Patients With Asthma
n=58 Participants
34 patients aged 7 to 18 years, and 24 patients aged 2 to 6 years Not an interventional study
Inter-rater Reliability for the Pediatric Respiratory Assessment Measure (PRAM)
28 percentage of agreement between raters

PRIMARY outcome

Timeframe: 4 years and 9 months

The intra-rater reliability between HASS and PRAM as scored by 2 individual health care providers. Intra-rater agreement refers to the with-in rater agreement between the PRAM and HASS categorical ratings. This was calculated separately for Rater 1 and Rater 2. The intra-rater agreement for Rater 2 was calculated by pooling the data from the Rater 2 clinicians.

Outcome measures

Outcome measures
Measure
Pediatric Patients With Asthma
n=58 Participants
34 patients aged 7 to 18 years, and 24 patients aged 2 to 6 years Not an interventional study
Intra-rater Reliability Between HASS and PRAM
Rater 1
71 percentage of agreement between raters
Intra-rater Reliability Between HASS and PRAM
Rater 2
64 percentage of agreement between raters

PRIMARY outcome

Timeframe: 4 years, 9 months

Population: There were 29 patients out of 58 that performed spirometry and therefore were able to be analyzed for this data.

The correlation coefficient between the HASS tool and FEV1 measurements.

Outcome measures

Outcome measures
Measure
Pediatric Patients With Asthma
n=29 Participants
34 patients aged 7 to 18 years, and 24 patients aged 2 to 6 years Not an interventional study
Correlation Between the HASS and Forced Expiratory Volume in 1 Second (FEV1)
-.31 correlation coefficient

PRIMARY outcome

Timeframe: 4 years 9 months

Population: There were 29 patients out of 58 that performed spirometry and therefore were able to be analyzed for this data.

The correlation between the PRAM and FEV1

Outcome measures

Outcome measures
Measure
Pediatric Patients With Asthma
n=29 Participants
34 patients aged 7 to 18 years, and 24 patients aged 2 to 6 years Not an interventional study
Correlation Between the PRAM and FEV1
-.30 correlation coefficient

Adverse Events

Pediatric Patients With Asthma

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Leah Abecassis

Boston Children's Hospital

Phone: 6173552299

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place