Program Cell Death Receptor 1 in Mycobacterium Avium Complex Lung Disease
NCT02779049 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 112
Last updated 2016-12-15
Summary
1. To understand the components of PBMC in MAC-LD patients, including T cells, B cells, nature killer cells, and monocyte.
2. To confirm the phenomenon of reduced PBMC response in MAC-LD patients
3. To study the proportion of apoptosis and PD-1 expression in T cells among MAC-LD patients, MAC colonizers, patients with tuberculosis, and healthy controls.
4. To study the apoptosis and PD-1/PD-L1 expression in T cells/macrophage from bronchial lavage among MAC-LD patients, MAC colonizers, patients with tuberculosis,
5. To examine the PD-1 gene polymorphism and the correlation with MAC-LD.
Conditions
- Mycobacterium Avium
Interventions
- OTHER
-
Blood examination
blood sampling
Sponsors & Collaborators
-
National Taiwan University Hospital
lead OTHER
Principal Investigators
-
Chin-Chung Shu, MD · National Taiwan University Hospital
Eligibility
- Min Age
- 20 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2015-01-31
- Primary Completion
- 2016-07-31
- Completion
- 2016-07-31
Countries
- Taiwan
Study Locations
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