The Effect of Dexamedetomidine for Interscalene Brachial Plexus Block on Plasma Biomarkers After Rotator Cuff Repair
NCT02766556 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50
Last updated 2016-05-10
Summary
The present study was designed to test the hypothesis that dexmedetomidine added to ropivacaine for interscalene brachial plexus blocks for elective shoulder surgery would enhance the duration and effect of analgesia when compared with ropivacaine alone, and their influence on serum IL-6, cortisol, IL-1beta, IL-8, and substance p.
Conditions
Interventions
- DRUG
-
dexmedetomidine
ISB with ropivacaine with dexmedetomidine or normal saline
- PROCEDURE
-
ISB
ISB with ropivacaine with dexmedetomidine or normal saline
- DRUG
-
Ropivacaine
ISB with ropivacaine with dexmedetomidine or normal saline
Sponsors & Collaborators
-
Chuncheon Sacred Heart Hospital
lead OTHER
Principal Investigators
-
Jae Jun Lee, M.D. · Department of Anesthesiology and Pain medicine, Chuncheon Sacred Heart Hospital, College of Medicine, Hallym University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- SUPPORTIVE_CARE
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 20 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2014-08-31
- Primary Completion
- 2015-08-31
- Completion
- 2016-01-31
More Related Trials
-
Dose Response Study of Dexamethasone in Combination With Bupivacaine 0.25%
NCT01690663 ·Status: COMPLETED ·Phase: NA
-
Prolongation of Pain Free Time by the Use of Dexamethasone in Peripheral Nerve Blockade
NCT02178449 ·Status: UNKNOWN ·Phase: PHASE4
-
Interscalene Block With Low-dose IV vs. Perineural Dexamethasone for Shoulder Arthroscopy
NCT02506660 ·Status: COMPLETED ·Phase: PHASE4
-
Analgesic Efficacy of Perineural Dexamethasone During Supraclavicular Block for Hand Surgery
NCT02154048 ·Status: TERMINATED ·Phase: PHASE2
-
Ultrasound-guided Thoracic Paravertebral Block Using Ropivacaine With/Without Dexamethasone in Elective Thoracotomy
NCT02871193 ·Status: COMPLETED ·Phase: NA
-
Dexmetomidine Intrathecally and Intravenously Additionally to Spinal Anaesthesia, in Total Knee Arthroplasty
NCT02966249 ·Status: UNKNOWN ·Phase: PHASE4
-
Thoracic Paravertebral Blocks Using a Combination of Ropivacaine and Dexmedetomidine
NCT03677115 ·Status: WITHDRAWN ·Phase: PHASE4
-
Liposomal Bupivacaine With Standard Bupivacaine Versus Dexmedetomidine With Standard Bupivacaine
NCT06235606 ·Status: COMPLETED ·Phase: PHASE3
-
Dexmedetomidine and Morphine as Adjuvants to US Guided Erector Spinae Plane Blocks in Elective Thoracic Surgeries
NCT05843344 ·Status: UNKNOWN ·Phase: NA
-
Preemptive Co-infiltration of Dexamethasone Palmitate With Ropivacaine for Postoperative Pain in Major Spinal Surgery
NCT05693467 ·Status: COMPLETED ·Phase: PHASE4
-
Superficial Cervical Plexus Block With Dexmedetomidine Versus Without Adjuvant in Thyroid Surgery
NCT07274670 ·Status: COMPLETED ·Phase: NA
-
Minimal Effective Concentration (EC90) of Ropivacaine
NCT03688269 ·Status: COMPLETED ·Phase: PHASE3
-
The Effect of Dexamethasone on the Duration of Interscalene Nerve Blocks With Ropivacaine or Bupivacaine
NCT00801138 ·Status: TERMINATED ·Phase: NA
-
Liposomal Bupivacaine vs Dexamethasone ISB
NCT04047446 ·Status: COMPLETED ·Phase: PHASE4
-
Dexamethasone Added to Levobupivacaine Improves Postoperative Analgesia
NCT01739270 ·Status: UNKNOWN ·Phase: NA
-
Quality of Analgesia After Interscalene Block After Arthroscopic Shoulder Surgery
NCT02554357 ·Status: COMPLETED ·Phase: NA
-
Liposomal Bupivacaine Plus Bupivacaine Peripheral Nerve Blockade Versus Ropivacaine Plus Dexamethasone Peripheral Nerve Blockade for Arthroscopic Rotator Cuff Repair
NCT04737980 ·Status: COMPLETED ·Phase: PHASE4
-
Dexmedetomidine Combined With Bupivacaine in Ultrasound-guided Pecto-Intercostal Fascial Block in Cardiac Surgery
NCT07023874 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Efficacy of Adding Dexmedetomidine in Ultrasound-guided Intermediate Cervical Plexus Block for Thyroidectomy Surgery
NCT05814744 ·Status: COMPLETED ·Phase: NA
-
Effect of Dexmedetomidine on the Duration of Pain Control in ESP Block for Breast Surgery
NCT04029467 ·Status: UNKNOWN ·Phase: PHASE4
-
Comparison of Analgesic Efficacy Between of Interscalene Block With Liposomal Bupivacaine With Bupivacaine and Dexamethasone
NCT03969875 ·Status: COMPLETED
-
Effects of Methylprednisolone Plus Ropivacaine Infiltration Before Wound Closure on Laminoplasty or Laminectomy
NCT04493463 ·Status: COMPLETED ·Phase: PHASE4
-
Perineural Low-dose Dexamethasone Added to Infraclavicular Block Anesthesia
NCT02698995 ·Status: COMPLETED ·Phase: PHASE3
-
Interscalene Block and Dysfunction Diaphragmatic
NCT04173364 ·Status: COMPLETED ·Phase: PHASE3
-
Comparing the Effect of Adding Dexmedetomidine to Bupivacaine in Classical and Modified Thoracolumbar Interfascial Plane Block on Postoperative Pain in Patients Undergoing Lumbar Disc Surgeries
NCT06690021 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4