Haploidentical Hematopoietic Stem Cell Transplantation for Acute Leukemias
NCT02759822 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 30
Last updated 2016-05-03
Summary
This is a prospective observational cohort study of haploidentical transplantation with post-transplant cyclophosphamide for acute leukemias using reduced intensity conditioning for acute myeloid leukemia (AML) and myeloablative conditioning for acute lymphoblastic leukemia (ALL).
Conditions
- Leukemia, Myeloid, Acute
- Precursor Cell Lymphoblastic Leukemia-Lymphoma
Interventions
- PROCEDURE
-
Haploidentical Stem Cell Transplantation
Haploidentical Stem Cell Transplantation from a related donor (partially matched sibling, father, mother, son or daughter).
Sponsors & Collaborators
-
Leonardo Javier Arcuri
lead OTHER_GOV
Principal Investigators
-
Leonardo J Arcuri, MD · Instituto Nacional de Cancer
Eligibility
- Min Age
- 1 Year
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-04-30
- Primary Completion
- 2021-04-30
Countries
- Brazil
Study Locations
More Related Trials
-
Feasibility and Outcomes of Allogeneic HCT Compared to Chemotherapy in Older AML Patients
NCT01929408 ·Status: COMPLETED
-
Ex Vivo T-Cell-Depleted Haploidentical Transplantation Bridging With Chimeric Antigen Receptor T-cell Therapy and Prophylactic Memory T Cell Infusion for Acute Leukemia
NCT07087847 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Chemotherapy Followed by Infusion of Partially HLA Matched Unrelated Donor Cells for Patients With AML Who Are Ineligible for Stem Cell Transplantation
NCT02189824 ·Status: UNKNOWN ·Phase: PHASE1
-
Clinical Registration Study of Haplo-HSCT for Elderly Patients With Acute Leukemia/ Myelodysplastic Syndrome
NCT05902416 ·Status: RECRUITING
-
Haplo HCT vs Haplo-cord HCT for Patients With AML
NCT03719534 ·Status: COMPLETED ·Phase: PHASE3
-
De-escalated Treatment Approach for Adult Ph-negative Acute Lymphoblastic Leukemia (ALL)
NCT03462095 ·Status: UNKNOWN ·Phase: NA
-
A 3-cohort Randomized Study Evaluating the Role of New Immunotherapeutic Agents and of Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) in Frontline Therapy of Adults With Acute Lymphoblastic Leukemia
NCT06860269 ·Status: RECRUITING ·Phase: PHASE2/PHASE3
-
Up-front Hematopoietic Stem Cell Transplantation in Acute Myeloid Leukemia Patients Aged 65-75
NCT03902665 ·Status: COMPLETED ·Phase: PHASE2
-
Multicenter Study of Combined Chemotherapy and Transplantation for Adult ALL
NCT07059156 ·Status: RECRUITING ·Phase: PHASE2/PHASE3
-
Donor Stem Cell Transplant in Treating Young Patients With Acute Myeloid Leukemia With Monosomy 7, -5/5q-, High FLT3-ITD AR, or Refractory or Relapsed Acute Myelogenous Leukemia
NCT00553202 ·Status: COMPLETED ·Phase: PHASE2
-
Thiotepa, Cyclophosphamide, Clarithromycin and Cytarabine
NCT06060782 ·Status: RECRUITING ·Phase: PHASE1
-
Adult Acute Lymphoblastic Leukemia Treated With Pediatric Regimen in Brazil
NCT05959720 ·Status: RECRUITING
-
Allogeneic Stem Cell Transplantation in Chronic Lymphocytic Leukemia
NCT00337519 ·Status: UNKNOWN ·Phase: PHASE2
-
Mitoxantrone Hydrochloride Liposome Combined With BU/Cy Were Used as a Conditioning Regimen for Patients With Intermediate/Adverse Risk or Persistently Positive MRD AML
NCT06758726 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Prospective, Single-arm, Multicenter Clinical Study on Haploidentical Hematopoietic Stem Cell Transplantation in Patients With MRD Positive CD19+ALL Treated With Conditioning Regimens Containing Blinatumomab
NCT06125106 ·Status: RECRUITING ·Phase: PHASE1
-
Hematopoietic Stem Cell Microtransplantation for in AML
NCT02676856 ·Status: UNKNOWN ·Phase: NA
-
Treatment of Adult ALL With an MRD-directed Programme.
NCT00358072 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy of Acute Lymphoblastic Leukemia-Based Therapy in Treating Patients With Acute Leukemia of Ambiguous Lineage
NCT04440267 ·Status: RECRUITING ·Phase: PHASE2
-
Master Framework For Relapse or Refractory Acute Myeloid Leukemia
NCT06459024 ·Status: RECRUITING
-
Microtransplantation in Older Patients With Acute Myeloid Leukemia
NCT02831192 ·Status: COMPLETED ·Phase: PHASE2
-
Donor Stem Cell Transplant in Treating Patients With High Risk Acute Myeloid Leukemia
NCT01801046 ·Status: TERMINATED ·Phase: PHASE1
-
High-dose Cytarabine and Survival in AML
NCT01034839 ·Status: COMPLETED
-
Monitoring Minimal Residual Disease of Patients With Acute Myelogenous Leukemia or High Grade Myelodysplastic Syndrome
NCT01311258 ·Status: RECRUITING
-
MRD/Risk-oriented Therapy of Adult Ph- ALL Including Pegylated Asparaginase and Lineage-targeted Methotrexate
NCT02067143 ·Status: COMPLETED ·Phase: PHASE2
-
Treatment of Elderly AML Patients With Induction Chemotherapy Followed by G-CSF-Mobilized Stem Cells From Haploidentical Related Donors
NCT02519712 ·Status: TERMINATED ·Phase: NA