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Changes in Inflammatory Markers During Pulmonary Rehabilitation Based on Exacerbation States in COPD

NCT02740686 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 85

Last updated 2018-10-19

No results posted yet for this study

Summary

This study will examine the inflammatory response to exercise encompassed as part of a standard pulmonary rehabilitation programme in patients with chronic obstructive pulmonary disease (COPD). Patients will be split into two groups, frequent exacerbators or infrequent exacerbators, dependent upon exacerbation history to compare responses to pulmonary rehabilitation amongst phenotypes.

Conditions

Interventions

OTHER

Sample collection

Frequent exacerbators and infrequent exacerbators will have blood and sputum samples obtained around pulmonary rehabilitation. No other intervention will be administered. Healthy controls will have resting blood samples taken.

Sponsors & Collaborators

  • National Health Service, United Kingdom

    collaborator OTHER_GOV

  • University of Lincoln

    lead OTHER

Principal Investigators

  • Alex R Jenkins, MPhil · PhD student

Eligibility

Min Age
40 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-07-31
Primary Completion
2018-08-28
Completion
2018-08-28

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02740686 on ClinicalTrials.gov