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Long Term Effects of Tyrosine Kinase Inhibitor Therapy on Ovarian Reserve and Fertility in Patients With Chronic Myeloid Leukemia or Gastrointestinal Stromal Tumor

NCT02734823 · Status: WITHDRAWN · Type: OBSERVATIONAL

Last updated 2024-03-18

No results posted yet for this study

Summary

This pilot research trial studies the long term effects of tyrosine kinase inhibitor therapy on ovarian reserve and fertility in patients with chronic myeloid leukemia or gastrointestinal stromal tumor. Studying ovary imaging, ovarian reserve markers, and hormone levels from patients receiving tyrosine kinase inhibitor therapy may help doctors learn more about the effects of tyrosine kinase inhibitor therapy on ovarian function and fertility.

Conditions

  • Chronic Myelogenous Leukemia, BCR-ABL1 Positive
  • Gastrointestinal Stromal Tumor
  • Premenopausal

Interventions

OTHER

Cytology Specimen Collection Procedure

Undergo collection of serum

OTHER

Laboratory Biomarker Analysis

Correlative studies

OTHER

Questionnaire Administration

Ancillary studies

PROCEDURE

Ultrasonography

Undergo transvaginal pelvic ultrasonography

Sponsors & Collaborators

  • National Cancer Institute (NCI)

    collaborator NIH

  • University of Southern California

    lead OTHER

Principal Investigators

  • Irene Woo · University of Southern California

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-03-01
Primary Completion
2024-03-14
Completion
2024-03-14

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02734823 on ClinicalTrials.gov